ISSN:
1432-2072
Keywords:
Cannabis
;
Lysergic Acid Diethylamide
;
Mescaline
;
Hallucinogens
;
Psychopharmacology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Using climbing rope and bar-pressing behavior methods, rats were rendered tolerant to Δ 9-THC, cannabis extract, mescaline and LSD-25. Cross-tolerance experiments showed that rats refractory to Δ 9-THC and cannabis extract were still sensitive to mescaline and LSD-25, and vice-versa. These results suggest that, in spite of the similarity of the clinical symptoms produced in man by the 3 drugs, Δ 9-THC may have its psychotomimetic effects produced by different mechanisms from those of LSD-25 and mescaline.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00414344
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