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  • 1965-1969  (9)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 16 (1969), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Myelin was isolated from bovine optic nerves by differential ultracentrifugation and its lipid composition was analysed. Optic nerve myelin contained 76·3 per cent lipid. The major lipids were cholesterol, ethanolamine glycerophosphatides (EGP) and cerebroside. Serine glycerophosphatides (SGP), sphingomyelin and cerebroside sulphate were present in smaller proportions. EGP and SGP contained 34·6 and 0·5 per cent aldehydes. The major fatty aldehydes were palmitaldehyde, stearaldehyde and octadecenaldehyde. The fatty acids of EGP, SGP and choline glycerophosphatides (CGP) were chiefly 16:0, 18:0 and 18:1, with small proportions of 20 and 22 carbon polyunsaturates. The sphingolipids contained predominantly saturated and monounsaturated fatty acids of chain lengths of 20–26 carbon atoms. Optic nerve myelin and white matter myelin resembled one another closely in overall lipid composition and in the fatty acid compositions of their constituent lipids. Optic nerve myelin and white matter myelin are chemically similar membranes, but both of these differ in their lipid composition from spinal root myelin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 15 (1968), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Cardiolipin (diphosphatidyl glycerol) was isolated from bovine brain grey matter in pure form by column chromatography. A combination of a DEAE cellulose column, an acid-silicic acid column and a bicarbonate-treated silicic acid column was used for the isolation. Analytical data on cardiolipin (and lyso-cardiolipin), including phosphorus and fatty ester values, infrared and ultraviolet spectra, and chromatographic behaviour of intact cardiolipin, lyso-cardiolipin and their water-soluble hydrolysis products gave results which were consistent with the diphosphatidylglycerol structure proposed by MacFarlane. Cardiolipin constituted 1·2 per cent of the total lipids from grey matter, or 0·43 per cent of the dry weight. No aldehydes were detected in purified cardiolipin. The major fatty acids were 16:0, 16:1, 18:1, 18:2 and 20:4. Cardiolipin contained much higher concentrations of 18:2 (17·8 per cent) than any of the other major grey matter glycerophosphatides. Cardiolipin was hydrolysed by incubation with snake venom (Trimeresurus flavoviridis) phospholipase A (phosphatide acyl-hydrolase, EC 3.1.1.4) to determine the distribution of fatty acids on the carbons of its diglyceride moieties. The fatty acids were not distributed randomly; 16:0, 18:0 and 18:2 were predominantly localized in the α and α positions, while 18:1 and 20:4 were predominantly localized in the β and β positions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 17 (1966), S. 275-290 
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of medicinal chemistry 12 (1969), S. 1112-1112 
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Inorganic chemistry 7 (1968), S. 1664-1665 
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 212 (1966), S. 1057-1058 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Potassium uptake by the human platelet is not inhibited by either iodoacetate or by potassium cyanide3, but platelets incubated with both enzyme inhibitors together cannot take up potassium. Gorstein and Carroll conclude that platelets can obtain energy for potassium transport from either ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Meteorology and atmospheric physics 16 (1967), S. 267-272 
    ISSN: 1436-5065
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Description / Table of Contents: Zusammenfassung Es wird gezeigt, daß der Cornu-Test und der Test mittels des Schiefekoeffizienten anderen Tests vorzuziehen sind, wenn man prüft, ob kleine Stichproben mit weniger als 100 Beobachtungen aus einer Normalverteilung stammen. Das von Cornu verwendete Verhältnis zwischen der mittleren Abweichung und der Streuung ist stark negativ mit dem Exzeßkoeffizienten korreliert.
    Abstract: Résumé On démontre ici que le test de Cornu et celui du coefficient d'obliquité est préférable à tout autre lorsqu'il s'agit d'examiner si de petits échantillons de moins de 100 observations proviennent d'une répartition normale. Le rapport utilisé par Cornu entre l'écart moyen et l'écart quadratique moyen est corélé d'une manière fortement négative avec le coefficient de l'excès.
    Notes: Summary The Cornu criterion and the coefficient of skewness test are shown to be preferable to other tests when testing the hypothesis that small samples, less than 100, have been obtained from a normal population. The Cornu ratio of mean deviation to standard deviation is highly negatively correlated with the coefficient of kurtosis.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 207 (1965), S. 306-307 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Zucker and Zaccardi1 have claimed that platelets change their shape and become more nearly spherical when exposed to adenosine diphosphate (ADP). This observation can be substantiated and studied in some detail by the following technique. Fresh heparinized or citrated platelet-rich human plasma is ...
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The diphenol 1 was resolved into its antipodes and their absolute configuration was established. The levorotatory isomer R-(-)-1 was oxidized to the dienone R-(-)-6, which was rearranged to afford natural (-)-multifloramine (R-(-)-7), thus establishing that the latter has the R-configuration. By the same reaction sequences, the enantiomeric diphenol S-(+)-1 was transformed to provide (+)-multifloramine (S-(+)-7) of the S-configuration.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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