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  • 1965-1969  (3)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Protection and host cell repair of irradiated lambda phage (1969)
    Springer
    Molecular genetics and genomics 104 (1969), S. 142-146 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Phage λ, irradiated with ultraviolet light in the presence and absence of the free-radical scavenger and proton donor, cysteamine, have been assayed on normal and DNA-repair deficient bacteria. It has, been concluded that cysteamine protects the phage against lesions of a type which can be repaired by the bacterial DNA-repair systems. Presumably, these are pyrimidine dimers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272794
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Protection and host cell repair of irradiated lambda phage (1969)
    Springer
    Molecular genetics and genomics 104 (1969), S. 147-151 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Phage λ, in which thymine has been totally substituted by the analog, 5-bromouracil, have been irradiated with near visible light in the presence and absence of cysteamine, a free radical scavenger and proton donor. These phage were then assayed on normal bacteria and on mutants which are unable to repair DNA lesions. It is concluded that these phage suffer three different kinds of lesions: (1) a class which are not reparable, but which can prevented cysteamine, suggesting that they are sugar damages; (2) a class which are reparable but are not eliminated by cysteamine and (3) a class which can be neither eliminated nor repaired. The nature of the latter two types of lesions cannot be surmised at present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272795
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Protection and host cell repair of irradiated lambda phage (1969)
    Springer
    Molecular genetics and genomics 104 (1969), S. 152-156 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary 5-bromouracil-containing λ phage, irradiated with UV light in the presence and absence of cysteamine, were assayed on normal and DNA-repair deficient bacteria. It has been found that these phage suffer (1) lesions, of unknown nature, which are neither reparable by the bacterial DNA repair systems nor prevented by cysteamine, a free radical scavenger and proton donor; (2) lesions which are converted to reparable lesions by cysteamine, and which may be sugar damages (perhaps accompanied by pyridimine dimers) which are converted to simple dimers; and (3) irreparable lesions, which do not occur in the presence of cysteamine, and which are probably sugar damages. These latter are the most important, and in large part explain the increased sensitivity to irradiation of 5-bromouracil-substituted phage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272796
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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