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  • 1960-1964  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 17 (1961), S. 572-573 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Ischämie ruft in der Kleinhirnrinde eine ähnliche Depolarisation hervor wie in der Grosshirnrinde. Durch lokale KCl-Applikation erhält man in der Kleinhirnrinde langsame Potentialwellen, die in Amplitude und Ausbreitungsgeschwindigkeit der «spreading depression» vonLeão in der Grosshirnrinde entsprechen. Ischämie und lokale Applikation von 2,4-Dinitrophenol bewirken in beiden Rindengebieten gleiche Verschiebungen der Kaliumionen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 3 (1962), S. 254-263 
    ISSN: 1432-2072
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of physostigmine on EEG activity and conditioning was studied in rats. Theta activity develops in the hippocampus of curarized or freely moving unanesthetized animals 3–7 min after i.p. injection of 1 mg/kg physostigmine salicylate, attains maximum after 10 min and disappears after 30–60 min. Gradual impairment of learning corresponds to the development of theta waves. One-trial acquisition of a passive avoidance reaction (avoiding a compartment with electrifiable floor) is completely suppressed 10 min after application of 1.0 or 0.5 mg/kg physostigmine and to a lesser extent even after 0.2 mg/kg physostigmine. No retention of this reaction was found 24 h after onetrial learning when physostigmine (0.5 mg/kg) was applied 8 min before the retention test. On the contrary the same physostigmine dose does not impair the retention of an overtrained (four times) passive avoidance reaction. Also retention of an overlearned active avoidance reaction (running to the safe part of the apparatus is not affected by 0.5 mg/kg physostigmine and only partly impaired by 1 mg/kg physostigmine. The functional significance of the hippocampal theta activity is discussed.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 5 (1964), S. 255-263 
    ISSN: 1432-2072
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary EEG changes induced by intraperitoneal injection of 6 mg/kg atropine sulphate were studied in freely moving rats with implanted electrodes. Sleep-like high voltage slow wave activity appeared in neocortex, hippocampus and reticular formation attaining maximum approximately 20 minutes after atropine injection. At the height of the atropine effect one-trial learning of a passive avoidance reaction was partly impaired. So was extinction of this overtrained reaction. Atropine injected 20 minutes before the retention test adversely affected retrieval of threshold conditioned reactions; this effect could not be demonstrated with slightly overtrained behavior. Atropine impaired neither the consolidation nor the storage of memory traces. The atropine induced dissociation between EEG and behavior is discussed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Philadelphia : Wiley-Blackwell
    Journal of Cellular and Comparative Physiology 59 (1962), S. 155-161 
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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