ZIB

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

A Pharmacological Investigation of Potential Antidepressants of the Amitriptyline-Type (1963)

Stewart, Jane ; Charest, Marie-Paule ; Herr, Ferenc

s.l. : American Chemical Society

Journal of medicinal chemistry 6 (1963), S. 338-339

add to mindlist on the mindlist

Details

ISSN: 1520-4804

Source: ACS Legacy Archives

Topics: Chemistry and Pharmacology

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1021/jm00339a032

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Differential responses based on the physiological consequences of pharmacological agents (1962)

Stewart, Jane

Springer

Psychopharmacology 3 (1962), S. 132-138

add to mindlist on the mindlist

Details

ISSN: 1432-2072

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Rats were trained to make differential escape responses based solely on the different physiological states brought about by pharmacological agents. Two groups were trained to differentiate between saline and chlorpromazine while a third group was trained to differentiate between saline and imipramine. When the responses were well established “test drugs” were substituted for the “training drugs” in an attempt to determine the degree of transfer of the learned response from the “training drug” to the “test drug”. It was found that the chlorpromazine trained response transferred to acepromazine, perphenazine and prothipendyl, whereas there was no transfer from chlorpromazine to prochlorperazine or to imipramine at the doses studied. The imipramine trained response did not transfer to either chlorpromazine or acepromazine. The findings were discussed briefly in terms of the possible features of the physiological states which might be crucial in determining the results.