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  • 1
    Electronic Resource
    Electronic Resource
    The mortality and morbidity associated with umbilical cord prolapse (1995)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 102 (1995), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To examine the management of cord prolapse and its morbidity and mortality.Design Retrospective study of consecutive babies born after cord prolapse, identified using the Oxford Obstetric Data System, and those with registered handicap, identified by the Oxford Region Register of Early Childhood Impairments.Setting District maternity hospital managing more than 6000 deliveries annually.Subjects One hundred and thirty–two babies born after the identification of cord prolapse in the John Radcliffe Hospital between January 1984 and December 1992.Main outcome measures Survival rates, condition at birth assessed by Apgar scores at 1 and 5 minutes and blood gas values on cord blood samples, and incidence of major handicap at three years of age.Results The incidence of cord prolapse was 1 in 426 total births. There were six stillbirths and six neonatal deaths. One baby died as a result of birth asphyxia. The uncorrected perinatal mortality rate was 91 per 1000. Of 120 survivors, only one baby was known to suffer a major neurological handicap. Electronic cardiotocographs aided the diagnosis of cord prolapse in 41 % of cases. Apgar scores were better with a shorter diagnosis to delivery interval, but cord gas results did not correlate well with Apgar scores or the diagnosis to delivery interval.Conclusions Cord prolapse occurs with a relatively stable incidence in this population irrespective of changes in obstetric practices. Despite the high incidence of ominous cardiotocographs, low Apgar scores and acidaemia on blood gas analysis, the fetal outcome is not as poor as might be expected and mortality is predominantly attributable to congenital anomalies and prematurity rather than birth asphyxia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1995.tb10850.x
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  • 2
    Electronic Resource
    Electronic Resource
    Marked Amine and Amine Metabolite Changes in Norrie Disease Patients with an X-Chromosomal Deletion Affecting Monoamine Oxidase (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 54 (1990), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Urinary and plasma amines and amine metabolites were quantified in two individuals with Norrie disease resulting from a deletion in chromosomal region Xp 11.3, recently reported to be associated with absence of the gene encoding monoamine oxidase (MAO)-A and nondetectable MAO-A activity in fibroblasts and MAO-B activity in platelets. Marked (four- to 100-fold) elevations in levels of urinary phenylethylamine, o-tyramine, and m-tyramine (which are preferential substrates for MAO-B) and marked reductions (90%) in levels of 3-methoxy-4-hydroxyphenylglycol (a deaminated metabolite of norepinephrine, a preferential substrate for MAO-A) in urine and plasma confirmed the presence of a systemic, functionally significant reduction in the activities of both MAO isozymes. The magnitude of these changes, which are equivalent to those found in subjects taking MAO-inhibiting antidepressants, suggests that early initiation of dietary and drug restrictions may be clinically important in these and other patients with X-chromosomal mutations involving MAO. These findings further support the proposition that the MAOA and MAOB genes are located in close proximity on the X chromosome. Negligible changes in the metabolites of dopamine and serotonin raise the possibility that other metabolic pathways are of importance for their production, that dietary or intestinal bacterial sources contribute substantially to the presence of these amine metabolites in urine, or both.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1990.tb13307.x
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  • 3
    Electronic Resource
    Electronic Resource
    Emittance tailoring of electron beams for propagation in dense gas (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 4258-4267 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An intense relativistic electron beam injected into dense gas characteristically propagates in a self-pinched mode but is susceptible to the resistive hose instability. This convective instability typically leads to large amplitude beam motion and the disruption of propagation. Theory and computation suggest that, although resistive hose cannot be completely suppressed, its convective growth can be reduced by varying the average betatron oscillation frequency from head to tail in the beam pulse. We report here on experiments designed to implement this variation by tailoring the beam emittance using an ion-focused regime "conditioning'' cell. Conditioning effectiveness is assessed by using measured beam quantities to evaluate a detuning parameter η(t). This information is correlated with beam propagation measurements to determine the optimum conditioning for resistive hose suppression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.363385
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  • 4
    Electronic Resource
    Electronic Resource
    Use of an active wire Bθ cell for electron beam conditioning (1996)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 4249-4257 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The propagation of intense, relativistic electron beams in air is subject to the resistive hose instability. Conditioning the beam prior to injecting it into the air can extend its range by reducing the hose growth rate and by reducing the initial spatial perturbations that seed the hose instability. Experiments have been performed using the SuperIBEX accelerator (Ipeak=10–30 kA, E=4.5 MeV, 40 ns full width at half-maximum) to develop conditioning cells that suppress the hose. This paper describes the performance of an active wire Bθ cell that is used in conjunction with an ion focused regime (IFR) cell. The IFR cell detunes the instability by producing a head-to-tail radius taper on the beam. The wire cell maintains this radius taper while producing an emittance taper that is necessary to suppress the hose growth. In addition, the wire cell reduces the initial beam perturbations through the anharmonic centering force associated with the wire current and its azimuthal magnetic field Bθ. The ability of the Bθ cell to reduce the beam offset with a minimal increase in the beam radius gives it several advantages over the use of a simple, thick scattering foil to perform the radius taper to emittance taper conversion. The SuperIBEX beam propagation distance, in terms of the betatron oscillation scale length, was extended to ∼10λβ using these cells. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.363384
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  • 5
    Electronic Resource
    Electronic Resource
    Transport and centering of high current electron beams in neutral gas filled cells (1995)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 78 (1995), S. 3580-3591 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Conducting tubes filled with neutral gas at pressures between 0.001 and 0.1 Torr can be used to transport, to center, and to reduce the transverse oscillations of high current ((approximately-greater-than)10 kA) electron beams. Electron impact ionization of the gas leads to partial neutralization of the beam space charge allowing self-focused beam transport and phase-mix damping of injected beam oscillations. In addition, the presence of conducting walls helps center the beam in the transport tube. High current beams, transported through a 1.3 m long tube, were centered to within one-tenth of the beam radius and input transverse oscillations were damped to submillimeter values without significant current loss or emittance growth. Beam transport properties are examined as a function of injected current, gas pressure, and cell geometry. Experimental results are compared with a theoretical model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.359933
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  • 6
    Electronic Resource
    Electronic Resource
    The I-J Puzzle (1987)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Immunology 5 (1987), S. 405-427 
    Details
    ISSN: 0732-0582
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.iy.05.040187.002201
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  • 7
    Electronic Resource
    Electronic Resource
    Delivery in an obstetric birth chair: a randomized controlled trial (1991)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 98 (1991), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective— To determine whether nulliparae whose second stage of labour is conducted in an obstetric birth chair have a lower incidence of instrumental delivery than those using a conventional delivery bed.Design— Randomized controlled trial using sealed, opaque envelopes for allocation.Setting— Delivery ward in a busy teaching hospital.Patients— 1250 nulliparae with a singleton live fetus with cephalic presentation, without epidural anaesthesia, who had achieved full dilatation.Intervention— Intention to conduct second and third stages of labour in either the Birth-EZ chair or the conventional delivery bed, as randomly allocated.Main outcome measures— Primary measure: vaginal operative delivery; principal secondary measures: duration of second stage, perineal trauma, blood loss, women's views, and neonatal status.Results— Delivery in the birth chair did not result in a reduction in operative delivery, overall. However, there was a reduction in vaginal operative delivery for fetal heart rate abnormality. There was no beneficial effect on perineal trauma or puerperal perineal pain. Post-partum haemorrhage was more frequent in the birth chair group.Conclusions— Delivery in the birth chair does not offer any obvious advantage to women over delivery on a bed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1991.tb13453.x
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  • 8
    Electronic Resource
    Electronic Resource
    Deoxyribonucleic acid polymerase with rat liver ribosomes and smooth membranes. Purification and properties of the enzyme (1971)
    s.l. : American Chemical Society
    Biochemistry 10 (1971), S. 1981-1992 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00787a004
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  • 9
    Electronic Resource
    Electronic Resource
    Phase relationships and conductivity of the polymer electrolytes poly(ethylene oxide)/lithium tetrafluoroborate and poly(ethylene oxide)/lithium trifluoromethanesulfonate (1988)
    s.l. : American Chemical Society
    Macromolecules 21 (1988), S. 654-660 
    Details
    ISSN: 1520-5835
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ma00181a020
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  • 10
    Electronic Resource
    Electronic Resource
    A compact, four-way image splitter (1994)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 762-763 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A compact, four-way, optical image splitter is described which maintains equal intensity and equal optical path length in each arm of the apparatus. The four output beams are parallel with the input light beam.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1145101
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