ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Consecutive C- and N-alkylation of 1-methyl-4-cyano-piperidine (I) with 1,2-dichloro-ethane affords 1-methyl-4-cyano-quinuclidinium chloride (III). Upon heating this salt is converted into 4-cyanoquinuclidine (IV), from which 4-quinuclidine-carboxylic acid is obtained after hydrolysis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19540370611
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