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  • Children  (2)
  • Sophora leachiana  (2)
  • 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Two complex flavanones from the roots of Sophora leachiana
    Amsterdam : Elsevier
    Phytochemistry 30 (1991), S. 3773-3775 
    Details
    ISSN: 0031-9422
    Keywords: Leguminosae ; Sophora leachiana ; flavonostilbene ; leachianone B ; leachianone C ; roots
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0031-9422(91)80108-D
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Two complex flavanones from the roots ofSophora leachiana
    Amsterdam : Elsevier
    Phytochemistry 30 (1991), S. 3773-3775 
    Details
    ISSN: 0031-9422
    Keywords: Leguminosae ; Sophora leachiana ; flavonostilbene ; leachianone B ; leachianone C ; roots
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0031-9422(91)80108-D
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Lead exposure among 3-year-old children and their mothers living in a pottery-producing area (1983)
    Springer
    International archives of occupational and environmental health 52 (1983), S. 223-229 
    Details
    ISSN: 1432-1246
    Keywords: Urinary lead ; Coproporphyrin ; δ-Aminolevulinic acid ; Children ; Mothers ; Pottery production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The present study's aim was to compare the levels of lead exposure between 3-year-old children and their mothers in a pottery-producing area, and to assess the levels of lead exposure for 3-year-old children of the parents engaged in pottery-manufacturing work. For these purposes urinary lead, coproporphyrin, and 6-aminolevulinic acid were determined for the children and their mothers, living in a pottery-producing area and in a control area. The mean urinary lead was 9.3 to 10.8 μg/l for the mothers in the pottery-producing area and 10.6 μg/l for the children in the control area. In contrast, among the children in the pottery-producing area, those whose parents had been engaged in the pottery production had a much higher mean urinary lead of 13.6 to 15.8 μg/l. These results suggest that parental work related to lead contributes appreciably to lead exposure for children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00526521
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Home lead-work as a potential source of lead exposure for children (1983)
    Springer
    International archives of occupational and environmental health 53 (1983), S. 37-46 
    Details
    ISSN: 1432-1246
    Keywords: Lead ; Children ; Home lead-work ; Lead-containing housedust
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Health examinations for lead poisoning were made on 62 family members from 15 families of homes carrying on lead work, such as quench-hardening in a molten lead bath and type-printing, as work at home. The most interesting findings concern the occurrence of cases with an unduly high lead absorption among children, but not among adult family members other than home lead-workers. The home environments of the children with an unduly high lead absorption represented contamination with housedust high in lead contents. The ingestion of the contaminated housedust by hand-to-mouth is probably responsible for the excessive lead exposure of the affected children. The results of the present study suggest that contanimation of housedust with lead due to home lead-work constitutes a possible hazardous source of lead exposure for children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00406175
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system (1994)
    Springer
    Journal of neural transmission 98 (1994), S. 107-118 
    Details
    ISSN: 1435-1463
    Keywords: Uptake ; inhibition ; dopamine transporter ; 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline ; 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline ; 1,2-dimethyl-6,7-dihydroxyisoquinolinium ion ; neuroblastoma SH-SY5Y cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Uptake of catechol isoquinolines to dopamine cells was studied using human dopaminergic neuroblastoma SH-SY5Y cells. Only (R)-1,2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline [(R)-1,2-DiMeDHTIQ] was transported by dopamine uptake system, while (S)-1,2-DiMeDHTIQ, (R)- and (S)-1-methyl-6,7-dihydroxy-tetrahydroisoquinoline, and 1,2-dimethyl-6,7-dihydroxyisoquinolinum ion were not. Kinetical study showed that the uptake of (R)-1,2-DiMeDHTIQ followed the Michaelis-Menten equation, and the values of the Michaelis constant and the maximal velocity were obtained to be 102.6 ± 36.9 μM and 66.0 ± 2.8 pmol/min/mg protein. Dopamine was found to inhibit (R-1-DiMeDHTIQ uptake competitively. These results suggest that the selective uptake by dopamine transporter may account for the specific neurotoxicity of (R)-1,2-DiMeDHTIQ to dopamine neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01277014
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    Paper (German National Licenses)
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