ISSN:
1573-9171
Keywords:
homolytic oxoalkylation
;
heteroaromatic bases
;
lead tetraacetate
;
manganese triacetate
;
pyridine
;
quinoline
;
1-methylcyclobutanol
;
1-methylcyclopentanol
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The oxoalkylation of pyridine, 2-methyl-, 4-methyl-, 2,4-dimethyl-, 2,6-dimethylpyridines, quinoline, 4-methylquinoline, isoquinoline, and pyrazine with oxoalkyl radicals generated from 1-methylcyclobutanol or 1-methylcyclopentanol under the action of Pb(OAc)4 or Mn(OAc)3 has been carried out. The reaction products are isomers with 2-(6)- and 4-positions of the oxoalkyl group in theN-heteroaromatic ring. The isomer ratios have been determined as a function of the structure of theN-heteroaromatic compound and the reaction conditions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00698999
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