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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 275 (1983), S. 147-151 
    ISSN: 1432-069X
    Keywords: Keratinocyte ; ATP ; Adenylate cyclase ; Cyclic AMP ; Prostaglandin D2
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Primary cultures of adult human and guinea-pig keratinocytes were treated with various retinoids for up to 7 days. The cells were exposed to 3H-adenine and then challenged with several agonists of adenylate cyclase. 3H-labeled adenine nucleotides were extracted and 3H-cAMP purified chromatographically. All retinoids increased the formation of 3H-ATP from 3H-adenine and the conversion of 3H-ATP to 3H-cAMP by guinea-pig cells, the extent being dependent on the particular retinoid and agonist used. Human cells were relatively sensitive to isoproterenol and not to prostaglandins or histamine, but their response was little affected by retinoids. Guinea-pig cells were most sensitive to prostaglandins. The proliferogenic effects of retinoids on the latter cells may be mediated by increased sensitivity to agonists leading to generation of cAMP.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 344 (1992), S. 299-304 
    ISSN: 1434-601X
    Keywords: 11.30.-j ; 12.30.-s ; 14.80.Dq
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The expectation of the geometrical catamorphic representation of the quark-lepton families is that the parameters of the CKM matrix, in the Wolfenstein substitution, have the valuesA=p=1 and δ≃π/3. No conflict is found with the geometrical expectation which, furthermore, requires 107〈m t〈165 GeV/c2, consistent withW, Z phenomenology.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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