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  • 1
    Electronic Resource
    Electronic Resource
    New fast preparation of 123I labelled radiopharmaceuticals (1987)
    Springer
    European journal of nuclear medicine 13 (1987), S. 380-381 
    Details
    ISSN: 1619-7089
    Keywords: Kit labelling ; 123I labelled radiopharmaceuticals ; Cu(I) assisted nucleophilic exchange ; Reducing medium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new fast kit preparation of 123I labelled radio-pharmaceuticals such as IMP, HIPDM, MIBG and Hippuran is proposed. A radiochemical yield 〉99% is obtained at 100°C within 10–30 min. The new labelling procedure is based on the nucleophilic exchange in presence of Cu(I) and an excess of reducing agents. The four kit prepared 123I-radiopharmaceuticals have been used with success in clinical studies involving 400 patients. The proposed method is also compared with earlier described methods which, yielding labelled side products and 123I2, do not fulfill the requirements for kit labelling.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00253000
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The value of fentanyl/diazepam anesthesia for experimental operations (1991)
    Springer
    European archives of oto-rhino-laryngology and head & neck 248 (1991), S. 402-405 
    Details
    ISSN: 1434-4726
    Keywords: Sound thresholds ; Attenuating effects ; Fentanyl/diazepam anesthesia ; Respiratory depression ; Muscle tremors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fentanyl/diazepam anesthesia is an appropriate combination for surgical operations on the guinea pig, since it ensures definitive anesthesia and analgesia without respiratory depression. Comparative investigations with pentobarbital and urethane were carried out to check their applicability for electrocochleographic recordings. We found that fentanyl/diazepam combination anesthesia is more suitable for electrocochleographic investigations than pentobarbital. We were thereby able to prove that pentobarbital has an attenuating effect on electrocochleographic recordings in contrast to the findings reported in the available literature. For this reason, and because the lowest rates of animal morbidity occurred with fentanyl/diazepam, this combination anesthesia should be used preferentially for electrophysiological experiments in guinea pigs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01463563
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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