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  • 1
    ISSN: 1432-1076
    Keywords: Key words Cerebral blood flow ; Preterm infants ; Neurological outcome ; Brain development ; 133Xenon method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cerebral blood flow (CBF) studies have provided some insight into pathophysiological mechanisms of cerebral damage in newborn children; their value in predicting brain damage, however, remains elusive. The purpose of our study was to evaluate the role of CBF measurements in predicting developmental outcome in preterm neonates at 18 months. Preterm babies with a gestational age of less than 34 weeks and a birth weight of less than 1500 g (n = 71) were enrolled in the study. CBF was measured by the nonivasive intravenous 133Xe method on three different occasions. We classified our measurements into three groups: depending on the time when performed group 1: between 2 and 36 h (n = 52); group 2: between 36 and 108 h (n = 44); group 3: between 108 and 240 h (n = 41). At the age of 18 months neurodevelopment testing was performed according to the Bayley mental and motor scales. Surviving infants had a higher mean CBF over the three groups than non surviving children (15.2 ± 3.5 ml/100 g brain tissue/min vs 13.0 ± 2.1 ml/100 g brain tissue/min, P 〈 0.05). There was no correlation of CBF with mental or motor development in our study population in either of the three groups. Conclusion In preterm infants basal CBF is higher in surviving than in non surviving infants, but there is no correlation of resting CBF and later neurological outcome.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-3924
    Keywords: Schlüsselwörter Osteochondrosis dissecans ; Osteonekrose ; Kniegelenk ; Spongiosaumkehrplastik ; Retrograde Anbohrung ; Key words Ostechondritis dissecans ; Osteonecrosis ; Knee joint ; Cancellous bone cylinder ; Indirect drilling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Operative techniques for osteochondritis dissecans can be divided into direct and indirect types: The arthroscopic minimally invasive techniques of indirect drilling and refilling by use of a reversed cancellous bone cylinder are described. The therapeutic aim is early intervention before dissection in order to prevent secondary arthritic changes of the joint surfaces. The time for intervention refers mainly to the stage and dimension of the disease, its clinical appearance and the progression of the osteonecrotic process in X-ray and MR imaging.
    Notes: Bei der operativen Therapie der Osteochondrosis dissecans des Kniegelenks wird zwischen anterograden und retrograden Techniken unterschieden: Die arthroskopischen, minimalinvasiven retrograden Techniken der Anbohrung mit Kirschner-Drähten bzw. die Spongiosaumkehrplastik werden beschrieben. Das Therapieziel ist hierbei die frühzeitige Intervention vor Dissektion zur bestmöglichen Prävention von sekundär-arthrotischen Gelenkflächenschädigungen. Der Zeitpunkt für eine retrograde Defektanbohrung ergibt sich in Abhängigkeit vom Erkrankungsstadium bzw. -ausmaß aus dem klinischen Beschwerdeverlauf sowie aus einem Fortschreiten der osteonekrotischen Prozesse im nativ-radiologischen Bild und/oder im Gadolinium-MRT.
    Type of Medium: Electronic Resource
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