ISSN:
0009-2940
Keywords:
3,4-Bis(phosphanyl)pyrrolidines
;
Palladium complexes
;
Rhodium complexes
;
Asymmetric hydrogenation
;
Phosphanes, chiral
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Enantioselective Catalysis, IX[1]. - New Optically Pure 3,4-Bis(phosphanyl)pyrrolidines with Phenyl and Anisyl Groups Including Their Palladium and Rhodium ComplexesMethods for the synthesis of the diastereomeric mixture of the [P(R,S),3R,4R,P′(R,S)]1-1-(tert1-butoxycarbonyl)1-3,4-bis[(2-methoxyphenyl)phenylphosphanyl]pyrrolidines (2a, b, c) are described. For the chromatographic separation and purification of the ligand diastereomers we transformed them into the PdI21-complexes (10a, b, c). The structure of (PR,3R,4R,P′R)1-1-(tert1-butoxycarbonyl)1-3,4-bis[(2-methoxyphenyl)phenylphosphanyl]pyrrolidine-P,P′}diiodopalladium (10 b) was determined by X-ray diffraction. Treatment of the palladium complexes with KCN yielded the pure phosphanes. The rhodium complexes (11a, 11b, 11c), which can be used as catalysts in enantioselective hydrogenations, were obtained by reaction of [Rh(COD)2]BF4 with compound 2a, 2b, or 2c.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19931260505
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