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  • 1
    Electronic Resource
    Electronic Resource
    The process of ultrastructural changes from nuclei to apoptotic body (1998)
    Springer
    Virchows Archiv 433 (1998), S. 443-447 
    Details
    ISSN: 1432-2307
    Keywords: Key words Apoptosis ; Crescent-shaped spaces ; Ultrastructure ; Nivalenol ; Thymus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  There have been many reports on the formation of apoptotic bodies, but little is known about the cellular pathological processes and the morphological changes involved. We induced apoptotic cell death by administering nivalenol (NIV), a trichothecene mycotoxin produced by Fusarium species, and investigated the ultrastructural process of formation of apoptotic bodies. The thymus was examined by electron microscopy 6, 12, and 18 h after administration. Apoptotic cell death was induced in the thymus of NIV-treated mice. The nuclei became invaginated and pinched off to give fragments, and crescent-shaped spaces (CSS) were found around the nuclear envelopes of these cells at quite an early stage. In some of these spaces, myelin figures were observed. We divided the process of formation into four stages and characterized each of them. These are easily recognized in morphological stages and are also useful for clarifying the apoptotic mechanism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004280050272
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  • 2
    Electronic Resource
    Electronic Resource
    A case report on a minor contamination of nivalenol in cereals harvested in Canada (1988)
    Springer
    Mycopathologia 101 (1988), S. 157-160 
    Details
    ISSN: 1573-0832
    Keywords: Nivalenol ; deoxynivalenol ; zearalenone ; Canadian cereals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract An investigation for the occurrence of nivalenol (NIV), deoxynivalenol (DON) and zearalenone (ZEN) in cereals (ten wheat, one rye and one corn) harvested in Canada have been carried out using a procedure, which is rapid and sensitive for Fusarium mycotoxins. NIV, DON and ZEN were detected in 4, 9 and 9 out of ten wheat samples, and their average levels in the positives were 23 ng/g, 1257 ng/g and 9 ng/g, respectively. One rye and one corn were also contaminated with a minor amount of NIV. This is the first evidence for the natural occurrence of NIV in cereals grown in Canada, though its level was far less than DON.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00437032
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The synthesis of crowned phenoselenazinone derivatives (1992)
    Springer
    Monatshefte für Chemie 123 (1992), S. 849-852 
    Details
    ISSN: 1434-4475
    Keywords: 16H-2,5,8,11,14-Pentaoxacyclopentadecano[2,3-a]phenoselenazin-16-one ; 20-Chloro-16H-2,5,8,11,14-pentaoxacyclopentadecano[2,3-a]phenoselenazin-16-one ; 17-Bromo-16H-2,5,8,11,14-pentaoxacyclopentadecano[2,3-a]phenoselenazin-16-one ; 20-Chloro-17-bromo-16H-2,5,8,11,14-pentaoxacyclopentadecano[2,3-a]phenoselenazin-16-one
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Es wurden einige substituierte Kronen-Phenoselenazin-16-on-Derivate mittels Kondensation von substituierten Zink-2-aminobenzolselenolaten mit dem 1,4-Chinon von Benzo[15]krone-5 oder seinem Dibromid in alkoholischer Lösung dargestellt. Die Dehalogenierung der Bromselenazinone wurde ebenfalls untersucht.
    Notes: Summary Several substituted crowned phenoselenazin-16-one derivatives were prepared by condensation of substituted zinc 2-amino-benzeneselenolates with 1,4-quinone of benzo[15]crown-5 or its dibromide in alcoholic solution. The dehalogenation of the bromoselenazinones was also investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00812334
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    Paper (German National Licenses)
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