Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Analytical Chemistry and Spectroscopy  (24)
  • Tardive dyskinesia  (3)
  • 18F20  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 58 (1978), S. 117-124 
    ISSN: 1432-2072
    Schlagwort(e): Tardive dyskinesia ; Neuroleptics ; Dosage ; Sex ; Age
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The adult population of a large mental hospital was screened for tardive dyskinesia (TD). Approximately 11% of the hospital population showed signs of TD; females and the elderly were over-represented in the TD group. A representative sample of those with TD was selected and a control (non-TD) patient was chosen to match each of the TD subjects in age, sex, length of hospitalization, diagnosis, and race. The charts of these subjects were searched for any indices of brain damage and the complete psychotropic medication history was recorded. There was no difference between the TD and controls in the amount of psychotropics ingested, in the duration of administration, in the kinds of drugs, or in the organicity history. Women as a group, however, tended to have more polypharmacy than men. The role of neuroleptics in TD is discussed as well as other possible etiological factors.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Algebra universalis 28 (1991), S. 188-213 
    ISSN: 1420-8911
    Schlagwort(e): co-rectangular-band object in a category of algebras ; decomposition of an algebra as a coproduct ; sheaf or cosheaf of algebras on a Stone space ; bounded Boolean power of an object of a category ; Primary: 08B25 ; 18D35 ; 18F20 ; 20M17 ; secondary: 06E15 ; 18A30 ; 20M50
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract Conditions on a categoryC are studied which imply that every structure of rectangular band on an objectS ofC arises from a unique product decompositionS=S 1×S 2, especially in the case whereC is the opposite of a category of algebras. Sheaves on Stone spaces with values in opposites of categories of algebras are examined. The analog of the bounded Boolean power constructionR[B]* forR an object of a general category is described.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Algebra universalis 28 (1991), S. 153-187 
    ISSN: 1420-8911
    Schlagwort(e): action of a Boolean ring on a set, sheaf of sets on the spectrum of a Boolean ring, commuting rectangular band operations ; bounded Boolean power of a set or algebra ; least nontrivial hypervariety of algebras ; Primary: 06E15 ; 06E20 ; 18F20 ; secondary: 08A05 ; 08B25 ; 18C10 ; 20M50 ; 54H10
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract LetB be a Boolean ring (with 1),S a sheaf of sets on the Stone space Spec(B), andS the set of global sections of S. For everya εB ands, t εS, leta(s, t) denote the element ofS which agrees withs on the support ofa, and witht elsewhere. We set down identities satisfied by this ternary operationB×S×S→S (involving also the Boolean operations ofB). For a fixed Boolean ringB, we call a setS given with a ternary operation satisfying these identities aBset. The above construction is shown to give a functorial equivalence between sheaves of setsS on Spec(B) with nonempty sets of global sections, and nonemptyB-setsS. For any setA, the bounded Boolean powerA[B]* is the freeB-set onA. The varieties ofB-sets, asB ranges over all Boolean rings, constitute (together with one trivial variety) the least nontrivial hypervariety of algebras, in the sense of W. Taylor.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 56 (1978), S. 75-80 
    ISSN: 1432-2072
    Schlagwort(e): Clozapine ; Schizophrenia ; Tardive dyskinesia ; Parkinsonism ; Neutropenia ; Convulsions
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Clozapine, which has had limited clinical testing in the U.S.A., was evaluated in 12 chronic schizophrenic patients with tardive dyskinesia. Its antipsychotic activity was again demonstrated and it suppressed the symptoms of tardive dyskinesia with a marked rebound occurring in these symptoms when it was withdrawn; there was no rigidity or other Parkinsonian symptoms. However, out of a total of 12 patients, neutropenia (800 and 1120) occurred in two patients, convulsions in one patient, marked withdrawal effects in three patients, and a hypotensive collapse with atrial fibrillation in one patient. If these adverse effects are confirmed in a larger sample size, then despite the novel desirable effects of clozapine it would seem unlikely that it will gain widespread or routine use1.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 52 (1977), S. 257-261 
    ISSN: 1432-2072
    Schlagwort(e): Tardive dyskinesia ; Deanol
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Ten hospitalized chronic psychotic patients with symptoms of tardive dyskinesia were given deanol and placebo, each for 8 weeks following a double blind, crossover design. No psychotropic agents were administered during the trial. Improvement occurred in all patients during the first treatment phase regardless of which drug the patients received; seven patients were on deanol and three on placebo during this time. The possible reasons for this decrease were discussed. It was concluded that deanol may have contributed to the decline but that its effect on the disorder was not dramatic.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 6
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 19 (1996), S. 657-668 
    ISSN: 0935-6304
    Schlagwort(e): Chlorobiphenyl congeners ; Aroclors ; DB-XLB phase ; HP-5/HT-5 serial coupled phases ; GC-ECD ; GC-MS-SIM ; GC-Ion Trap MS ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Three HRGC systems (1: 30m DB-XLB capillary with MS-SIM detection; 2: 60m DB-XLB capillary with full-scan, ion-trap MS detection; and 3: Parallel dual-column DB-17 and series-coupled HP5/HT5 with ECD detection) were used to completely characterize multiple lots of 8 different-numbered Aroclor mixtures by quantitative calibration against 9 solutions containing primary standards of all 209 PCB congeners. Despite lower absolute sensitivity and more Aroclor congener coelutions than the dual-column ECD system, the MS systems enabled measurement of more congeners per Aroclor since their greater linear response range did not require dilution of samples and standards. Pairs of different lots of Aroclors 1248 and 1254 displayed markedly different proportions of congeners, and the 1254 pair displayed strong differences in the extent of ortho-chlorine substitution. The tables of congener weight percent distributions among Aroclors are more comprehensive and quantitatively precise than those of prior publications. However, the limitations of single-level calibration precluded measurement of all congeners to the ±10% accuracy desirable for establishing these Aroclors as secondary standards for comprehensive, quantitative congener-specific PCB analysis.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 7
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 22 (1999), S. 533-540 
    ISSN: 0935-6304
    Schlagwort(e): Chlorobiphenyl congeners ; Aroclor 1254 ; DB-XLB phase ; GC-MS-SIM ; PCB 126 ; toxic equivalency ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: ---Complete PCB congener distributions in a panel of Aroclor mixtures were previously obtained by combining data from several HRGC systems. In that study quantitation of minor components may have been unreliable due to single level calibration against high levels of individual congener standards. Two lots of Aroclor 1254 had markedly different congener distributions. In this study, the design and performance of a congener-specific PCB analysis method employing GC-MS-SIM detection of congeners separated on a DB-XLB capillary column are discussed. Quantitation is carried out against a 6-level inclusive standard curve of a mixture of 144 congeners found in Aroclors. A separate procedure to measure trace levels of PCB 126 in Aroclors using the same system, combined with levels initially acquired for other congeners, facilitates estimation of TEQ values (Toxic Equivalencies of the PCB mixtures to 2,3,7,8-TCDD). PCB congener profiles of 15 Aroclor 1254 mixtures are presented. These profiles show that the less common, high TEQ variety of Aroclor 1254 was manufactured by an atypical, two-stage chlorination process that was apparently used during the final 1% of Aroclor 1254 production (ca. 1974-1976).
    Zusätzliches Material: 5 Tab.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 8
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 22 (1999), S. 373-378 
    ISSN: 0935-6304
    Schlagwort(e): Electrophoresis ; electrophoretic mobilities ; CZE ; MEKC ; peptides ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: ---A computer model is presented for the prediction of the electrophoretic mobilities of peptides from physical constants derived from their amino acid sequences. The model assumes that the electrophoretic mobility can be represented by a product of four functions according to the relation:  lcomp= l(L)w(W)q(Q)c(CC), where L (a length parameter) is represented by the number of amino acid residues of the peptide, W (a width parameter) is represented by the average residue mass, Q = the charge of the peptide, and CC = the position of the center of charge relative to the center of mass. The model was used to calculate the electrophoretic mobilities of peptides in a 50 mM phosphate buffer at pH 2.5. Sixty-four test peptides ranging in size from 2 to 39 amino acid residues were used for this study. The calculated mobilities show excellent correlation with experimental measurements with a correlation coefficient greater than 0.98.
    Zusätzliches Material: 5 Tab.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 9
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 17 (1994), S. 753-755 
    ISSN: 0935-6304
    Schlagwort(e): Capillary electrophoresis ; Nitrosamines ; Subambient temperature ; syn and anti isomers ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The separation of a selected group of naturally occurring, heterocyclic nitrosoamino acids was achieved by capillary zone electrophoresis and the resolution of the syn and anti conformers improved as the temperature was lowered to 5 °C. The double peaks observed for each nitrosoamino acid are probably caused by the slow kinetics of conformational isomerism. The experimental setup consisted of a P/ACE 5510 electrophoresis system, a 57 cm polyacrylamidecoated capillary, and a 10 mM phosphate buffer, pH 7.2, containing 2 mM of 3-(N-N-dimethylmyristylammonio)propanesulfonate (DMMAPS) and 0.1% Tween 20. Our study shows that (a) the lower the temperature, the greater the resolution and the longer the migration times; and (b) different nitrosoamino acid conformers were resolved at different temperatures because of differences in the rate of isomerization. For example, the conformers of N-nitrosothiazolidine-4-carboxylic acid were partially resolved at 30 °C while those of N-nitrosoproline were well resolved at the same temperature.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 10
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 17 (1994), S. 102-103 
    ISSN: 0935-6304
    Schlagwort(e): HPLC ; Capillary electrophoresis (CE) ; Laser desorption mass spectrometry ; Synthetic peptides ; Purity determination ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...