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  • 24-hour ambulatory monitoring  (1)
  • Air space  (1)
  • outet obstruction  (1)
  • 1
    ISSN: 1573-2568
    Keywords: high-grade reflux esophagitis ; 24-hour ambulatory monitoring ; esophageal motility ; pathogenesis reflux esophagitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using conventional manometry and 24-hr ambulatory pressure and pH monitoring, we investigated esophageal motility and the esophageal motor response to reflux in 11 patients with reflux esophagitis Savary-Miller grade III and IV, and an age- and sex-matched group of 11 healthy controls. The patients had a significantly increased esophageal acid exposure. Conventional manometry showed a significantly decreased LES pressure and distal peristaltic amplitude in patients. The 24-hr monitoring yielded a significant decrease in peristaltic contraction duration and peristaltic propagation velocity in the patient group. Distal peristaltic amplitude was not decreased. Analysis of the contractions occurring in the 2-min period after each reflux episode showed a reduced number of contractions during the upright period, caused by a significantly decreased number of peristaltic contractions. During the supine period, there was a trend towards an increased number of contractions. It is concluded that esophageal motor activity and the response to reflux are impaired in patients with high-grade reflux esophagitis. However, the abnormalities found are only minor and are unlikely to play an important role in the pathogenesis of reflux esophagitis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 38 (1993), S. 832-836 
    ISSN: 1573-2568
    Keywords: colon ; constipation ; gastric emptying ; outet obstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We wished to test the hypothesis that colonic loading with fecal material leads to delayed gastric emptying. Twelve healthy male volunteers were studied. Each of these subjects went through two randomized study periods of four days. In one of these, the subjects defecated upon urge, in the other period defecation was voluntarily suppressed. Gastric emptying of a semisolid meal (mashed potatoes) was measured with the noninvasive applied potential tomography technique. On day 3 no significant changes in gastric emptying were found, but on day 4 the emptying rate had decreased from 85.8±11.0%/hr (mean±sem) to 70.3±10.9%/hr (P〈0.05) and the T50 had increased from 38.5±3.4 min to 46.2±4.0 min (P〈0.025). The duration of the lag phase (4.1±1.5 min) was not significantly altered by suppression of defecation. Our conclusion is that voluntary suppression of defecation delays gastric emptying in normal subjects. This “cologastric brake” may be involved in the pathogenesis of upper abdominal symptoms in constipated patients.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1615-6102
    Keywords: Air space ; Cell wall ; Elastomer ; Intercellular space ; Microcasting ; Mung bean
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Infiltration of the intercellular gas space is often used in physiological experimentation either to reach internal targets with various biochemical probes or to extract molecules from the apoplast. Such investigations require a good understanding of the organization and structure of the gas space system. This system was studied in the mung bean hypocotyl using different approaches, in particular internal microcasting of seedlings. Results show the presence of two continuous, more or less independent, networks, one in the cortical parenchyma, the other in the pith. The narrow tubules of one or the other network connect all cells within a tissue. Infiltration with physiological solutions does not significantly disturb living cells, at least in the short term, but opens a large field for experimental applications.
    Type of Medium: Electronic Resource
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