ISSN:
1432-0738
Keywords:
Key words Epoxide hydrolase mRNA
;
Mouse
;
Peroxisome
;
Clofibrate
;
Hypolipidemic drug
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The soluble epoxide hydrolase mRNA level in liver was increased eight-fold upon administration of the hypolipidemic drug and peroxisome proliferator clofibrate for 7 days to mice. The soluble epoxide hydrolase mRNA was back at control levels within 1–2 days after clofibrate withdrawal. The highest expression was in liver, intestine and kidney. Lower levels were found in heart and muscle and very low levels were found in testes, lung, brain and spleen. The mRNA levels were increased in liver, kidney and heart by clofibrate.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002040050250
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