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  • 39B40  (1)
  • Combined treatment  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Interactions of mild hyperthermia, cisplatin and split dose irradiation in human ovarian carcinoma cells (1998)
    Springer
    Cancer chemotherapy and pharmacology 41 (1998), S. 491-496 
    Details
    ISSN: 1432-0843
    Keywords: Key words Hyperthermia ; Cisplatin ; Radiation ; Ovarian carcinoma ; Combined treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Human ovarian cancer cells were evaluated to determine whether combination treatment with mild hyperthermia and cisplatin could inhibit repair of sublethal radiation damage. Materials and methods: Human ovarian carcinoma cell lines A2780S (parental line) and A2780CP (cisplatin resistant variant) were used in this study. Cisplatin at concentrations of 1 or 3 μg/ml was given concomitantly with 1 h of heating at 40 °C either immediately before or after irradiation. Survival was determined using a colony-forming assay. Results: Neither mild hyperthermia nor cisplatin treatments alone affected sublethal damage repair. The combined treatment showed an effect in both cell lines and was treatment sequence-dependent. The effect was greater in the parental cell line. Conclusions: The data show that combined treatment of cisplatin and hyperthermia may have clinical efficacy at cisplatin concentrations and hyperthermia temperatures which by themselves have little to no effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002800050772
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    On Cauchy differences of all orders (1991)
    Springer
    Aequationes mathematicae 42 (1991), S. 137-153 
    Details
    ISSN: 1420-8903
    Keywords: 39B40 ; 39A70
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary This paper deals with the problem of characterizing higher order Cauchy differences of mappings on groups and semigroups. Symmetric, first order Cauchy differencesf(x + y)−f(x)−f(y) for mapsf between groups were characterized by Jessen, Karpf, and Thorup [8] through the use of first partial Cauchy differences. Our results are similar and extend their result to higher order differences. Our results also extend those of Heuvers [6] for mappings between vector spaces over the rationals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01818486
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    Paper (German National Licenses)
    Fulltext
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