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  • 42  (1)
  • 5-Hydroxytryptamine  (1)
  • Karyogamy  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of intracerebroventricular injection of clonidine on metabolic, respiratory, vasomotor and temperature responses in the rabbit (1981)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 315 (1981), S. 195-201 
    Details
    ISSN: 1432-1912
    Keywords: Clonidine ; 5-Hydroxytryptamine ; Hypothermia ; Metabolic rate ; Cutaneous vasodilatation ; Respiration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. The thermoregulatory outputs (including metabolic, respiratory and vasomotor activities) produced by an injection of clonidine or 5-hydroxytryptamine (5-HT) into the third cerebral ventricle of conscious rabbits were assessed at three different ambient temperatures (T a) of 2, 22 and 32°C. 2. When injected into the third cerebral ventricle, both clonidine and 5-HT produced a dose-dependent hypothermia in rabbits at both 2 and 22°C T a. The hypothermia was due to a decrease in metabolic heat production (M) at 2°C T a, while at 22°C T a the hypothermia was due to cutaneous vasodilatation. There were no changes in respiratory evaporative heat loss. 3. Furthermore, the clonidine-induced hypothermia was greatly reduced by pretreatment of the animals with either 5,6-dihydroxytryptamine (impairment of central 5-HT pathways) or yohimbine (alpha-adrenergic blocking agent), but not by 6-hydroxydopamine (impairment of central catecholamine pathways). 4. The results indicate that clonidine may act on the α-adrenergic receptors located on central 5-HT pathways to produce a hypothermic action by promoting a decrease in heat production or an increase in heat loss in the rabbit.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00499835
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  • 2
    Electronic Resource
    Electronic Resource
    Spectral Theory of Diffraction (1976)
    Springer
    Applied physics 10 (1976), S. 1-13 
    Details
    ISSN: 1432-0630
    Keywords: 84 ; 42 ; 10
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract In this paper we present an overview of the spectral domain approach for solving a variety of high frequency diffraction problems. We demonstrate via a number of examples that the fields derived from the use of the Spectral Theory of Diffraction (STD) remain uniformly valid for all observation angles, including the shadow boundary, the reflection boundary and the caustic direction where the conventional Geometrical Theory of Diffraction (GTD) breaks down. Furthermore, we show how the accuracy of STD can be improved and its range extended by combining it with integral equation methods in the spectral domain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00929524
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Occurrence of a parasexual cycle following the transfer of isolated nuclei into protoplasts of Phytophthora parasitica (1998)
    Springer
    Current genetics 34 (1998), S. 120-123 
    Details
    ISSN: 1432-0983
    Keywords: Key words Parasexual cycle ; Nuclear transfer ; Karyogamy ; Tetraploid formation ; Diploidization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Nuclei isolated from metalaxyl-resistant (Mr) protoplasts of Phytophthora parasitica were transferred into chloroneb-resistant (Cnr) protoplasts of the same species, with an average successful rate of 1×10–4, using a selective medium containing both metalaxyl and chloroneb. No colonies appeared when self-fusion products of donor nuclei or recipient protoplasts were exposed to the selective medium. Similar results were obtained when the reciprocal nuclear transformation was performed. All the zoospore cultures produced by nuclear transformants contained both Mr and Cnr genes, demonstrating the occurrence of karyogamy since most zoospores are uninucleate. An average of 38% of zoospores produced by nuclear transformants were about twice the size of normal zoospores. Each large zoospore contained a single nucleus, also about twice the size of that in normal zoospores, indicating the occurrence of tetraploidy in these zoospores. The other 42% of zoospores were of normal size but contained both Mr and Cnr genes, suggesting the occurrence of mitotic crossing-over following the production of tetraploidy and the subsequent occurrence of diploidization during zoosporogenesis. For the first time, this study demonstrated the completion of events leading to a parasexual cycle following nuclear transfer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050375
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    Paper (German National Licenses)
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