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  • 42.55  (3)
  • new FIR laser lines  (2)
  • Auranofin  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of infrared and millimeter waves 12 (1991), S. 449-471 
    ISSN: 1572-9559
    Keywords: waveguide CO2 lasers ; new FIR laser lines ; CH3OH ; 13CH3OH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have increased the frequency tunability of our CW waveguide CO2 lasers by means of an acoustooptic amplitude modulator, operating at the fixed frequency of 90 MHz. The up-shifted, or down-shifted, laser optical sideband can be generated independently by adjusting the orientation of the modulator. The efficiency is larger than 50%. The frequency tunability of the CO2 laser around each laser line is thus increased by 180 MHz. To demonstrate the possibilities of this method, a source composed of the above modulator and of a CW, 300 MHz tunable waveguide CO2 laser has been used for the search of new large offset FIR laser lines from optically pumped CH3OH and13CH3OH molecules. As a result 15 and 10 new large offset laser lines were discovered respectively. New assignments of some laser lines are also proposed. We have also measured the Stark effect, the offset, and the polarization of other already known lines. In particular a Stark effect frequency tuning of about 1 GHz is demonstrated for a laser line at 208.399 μm.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of infrared and millimeter waves 12 (1991), S. 557-571 
    ISSN: 1572-9559
    Keywords: Waveguide CO2 lasers ; new FIR laser lines ; CD3OH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract By using an acoustooptic modulator we extend the 300 MHz tunability of a waveguide CO2 laser to 480 MHz. The CD3OH was optically pumped by the 10R(32), 10R(34), and 10R(36) CO2 laser lines, and 17 new FIR laser lines were discovered. The Stark effect on previously known FIR laser lines was investigated, and some tentative FIR laser lines assignments are suggested.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 44 (1987), S. 111-117 
    ISSN: 1432-0649
    Keywords: 42.55
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The CD3OH molecule has been investigated for new far-infrared laser lines by optically pumping with a cw waveguide CO2 laser. The increased tunability (300 MHz) with respect to a conventional CO2 laser permits to pump many new CD3OH lines. As a consequence 108 new laser lines have been discovered, ranging from 42.9 to 1155 μm in wavelength. On some lines the effect of an electric Stark field has been investigated demonstrating a laser frequency tuning. The total number of known FIR laser lines from CD3OH is increased to about 340 making this molecule the most prolific together with CH3OH.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0649
    Keywords: 42.55
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We report new FIR laser lines from 13CH2F2 molecules optically pumped by a waveguide CO2 laser. The increased tunability (300 MHz) with respect to a conventional CO2 laser allows the pumping of 13CH2F2 vibrational transitions of large offset. 34 new laser lines have been discovered, ranging from 113.1 μm to 491.4 μm in wavelength, thus increasing the number of known FIR laser lines from this important molecule to 99. For all the new lines and many (36) of those known previously, precise offset measurements through the transferred Lamb-dip technique were performed. The frequency of six new laser lines was also directly measured by heterodyne detection with known laser lines.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0649
    Keywords: 42.55
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract By using high resolution infrared Fourier transform data on 13CD3OH and the 10P(22) and 10P(24) lines of a waveguide CO2 laser to optically pump this methanol isotope, eight new FIR laser lines were observed. The frequencies of five laser lines were directly measured by heterodyne detection with already known laser lines. Particularly interesting are the lines pumped by the 10P(24) line, since a triade of emissions could be completely assigned.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1434-9949
    Keywords: Auranofin ; Serum Conjugated Bile Acids ; Rheumatoid Arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several studies pointed out an altered stool pattern as the most common side effect of auranofin therapy. The major mechanism in the aetiology of auranofin-induced impairment in bowel habit seems to be the inhibition of Na+/K+ A TPase in the gut. In vitro experiments proved that auranofin can affect active bile acid (BA) reabsorption in rat terminal ileum; this action, due to the ability of the drug to reduce Na+ pump activity by inhibiting Na+/K+ATPase, may make a significant contribution to the auranofininduced diarrhoea. The ability of auranof in to reduce the Na+ gradient necessary for active BA reabsorption, however, could cause a decrease of serum BA levels in patients taking auranofin before or without the development of an overt diarrhoea. We measured fasting and postprandial serum conjugated BA levels in 10 female rheumatoid arthritis patients before and after one month and two months' auranofin treatment. No patient developed diarrhoea during the chrysotherapy. When oral gold salt therapy was started, we observed a slight decrease in serum BA levels, but difference was not statistically significant. We can conclude that auranofin therapy does not cause BA malabsorption in patients who do not develop diarrhoea during the treatment.
    Type of Medium: Electronic Resource
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