ISSN:
1432-1912
Keywords:
l-Tryptophan
;
5-Hydroxytryptamine
;
Electrolyte and water balance
;
Water intoxication
;
Antidiuresis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Under certain conditions the i.p. injection of l-tryptophan leads to a reduction of elimination of Na+. At the same time, the fractional Na+-reabsorption increases. No increase in the absolute tubular sodium transport rate was observed since the significantly reduced plasma-sodium concentration leads to a decreased sodium load. The most probable cause of a decreased plasma-sodium concentration seems to be a retention of sodium-free water under the chosen conditions of infusion. The water retention is compatible with the antidiuretic effect of 5-hydroxytryptamine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00509263
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