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  • 1
    ISSN: 1436-5057
    Keywords: 90C30 ; 65K05 ; Nonlinear programming algorithms ; penalty algorithms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Diese Arbeit beschreibt einen Algorithmus zur Minimierung einer nichtlinearen Funktion mit nichtlinearen Ungleichungen und Gleichungen als Nebenbedingungen. Die vorgeschlagene Methode hat die Eigenschaft, daß sie unter schwachen Voraussetzungen gegen einen Kuhn-Tucker-Punkt des betrachteten Optimierungsproblems konvergiert und unter stärkeren Voraussetzungen eine quadratische Konvergenzgeschwindigkeit aufweist. Ähnlich wie eine vor kurzem von Rosen vorgeschlagene Methode benutzt der Algorithmus eine Straffunktion, um einen Punkt in der Nähe der optimalen Lösung zu berechnen und schaltet dann auf Robinsons Methode um. Die neue Methode hat gegenüber dem Verfahren von Rosen zwei neue Eigenschaften. Erstens wird der richtige Wert des Parameters in der Straffunktion automatisch gefunden. Zweitens enthalten die mit der Methode von Robinson gelösten Teilprobleme nur lineare Gleichungen als Nebenbedingungen. Die Teilprobleme können daher besonders leicht gelöst werden. Vorläufige numerische Ergebnisse werden berichtet.
    Notes: Abstract This paper presents an algorithm for the minimization of a nonlinear objective function subject to nonlinear inequality and equality constraints. The proposed method has the two distinguishing properties that, under weak assumptions, it converges to a Kuhn-Tucker point for the problem and under somewhat stronger assumptions, the rate of convergence is quadratic. The method is similar to a recent method proposed by Rosen in that it begins by using a penalty function approach to generate a point in a neighborhood of the optimum and then switches to Robinson's method. The new method has two new features not shared by Rosen's method. First, a correct choice of penalty function parameters is constructed automatically, thus guaranteeing global convergence to a stationary point. Second, the linearly constrained subproblems solved by the Robinson method normally contain linear inequality constraints while for the method presented here, only linear equality constraints are required. That is, in a certain sense, the new method “knows” which of the linear inequality constraints will be active in the subproblems. The subproblems may thus be solved in an especially efficient manner. Preliminary computational results are presented.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0269-3879
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Antibodies against gangliosides isolated from small tumour and nervous tissue specimens can be reliably detected in serum samples by the ganglioside electrotransfer technique without the need for previous purification steps. After separation by high performance thin layer chromatography gangliosides are transferred from silica gel plates to hydrophobic polyvinylidene difluoride membranes. These membranes are highly suitable for immuno-staining. The use of a 15-slit device allows simulataneous testing of up to 15 serum samples. Samples of serum from 39 patients with clear-cell carcinoma of the kidney, mammary carcinoma, ovarian carcinoma and neurological disorder together with samples from healthy controls were tested for anti-ganglioside antibodies from various tissues.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 46 (1913), S. 2854-2864 
    ISSN: 0365-9496
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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