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  • 1
    Electronic Resource
    Electronic Resource
    Differential Regulation of IL-8 by IL-1β and TNFα in Hyaline Membrane Disease (1998)
    Springer
    Journal of clinical immunology 18 (1998), S. 71-80 
    Details
    ISSN: 1573-2592
    Keywords: Interleukin (IL)-1β ; tumor necrosis factor-α ; IL-8 ; hyaline membrane disease ; inflammation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mechanisms that regulate cytokine-mediated inflammation in the lungs of preterm infants, including factors which regulate production of the chemokine IL-8, remain poorly defined. Sequential bronchoalveolar lavage samples were obtained from preterm newborns with hyaline membrane disease over a 28-day period. Bronchoalveolar lavage cell cytokine relationships were evaluated and the differential regulation of IL-8 by IL-1β and TNFα was studied in a short-term culture system. In vivo, IL-8 and IL-lβ protein levels correlated closely with each other and with macrophage counts. In cell culture, exogenous anti-IL-1β antibody led to a 40% maximum inhibition (approximately) of IL-8 production by lipopolysaccharide stimulated lung inflammatory cells. Comparable amounts of exogenous anti-TNFα antibodies achieved a 15% maximum inhibition (approximately) of IL-8 production. Anti-IL-1β and anti-TNFα antibodies in combination did not inhibit IL-8 production beyond that achieved by anti-IL-lβ antibody alone. These results, in preterm newborns, support the concept of lung inflammation mediated in part by a macrophage, IL-1β, and IL-8 cell cytokine pathway. The results also suggest that factors other than IL-1β and TNFα regulate IL-8 expression in the lungs of preterm infants.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1023244005765
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    An investigation of catalytic activity in mixed metal oxide nanophase materials (1993)
    Springer
    The European physical journal 26 (1993), S. 46-50 
    Details
    ISSN: 1434-6079
    Keywords: 82.65.Jv ; 81.20.Lb
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present preliminary evidence for catalytic activity by unsupported mixed metal oxide nanocrystalline materials. The results of this study show that a nanophase form of Li-MgO has begun to exhibit catalytic activity by 300 °C. This is at least 200 degrees below the temperature at which conventional Li-MgO catalysts exhibit comparable activity. Furthermore, at higher temperatures, the same nanophase composition shows enhanced activities and somewhat improved hydrocarbon selectivities over conventional Li-MgO catalysts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01429104
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The Dynamical Effects of Hyperviscosity on Numerical Geodynamo Models (1998)
    Springer
    Studia geophysica et geodaetica 42 (1998), S. 247-253 
    Details
    ISSN: 1573-1626
    Keywords: convection ; hyperviscosity ; dynamos
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences , Physics
    Notes: Abstract The most fundamental difficulty in the construction of an Earth-like dynamo model is associated with the constraint caused by the rapid rotation of the Earth. To stabilise numerical codes, many workers have introduced hyperviscosity into the governing equations. One of the major effects introduced by hyperviscosity is to offset the rotational constraint, and, consequently, to alter the key dynamics of an Earth-like dynamo. In this paper, an Earth-like convection model with or without the presence of an imposed magnetic field is investigated with or without the effect of hyperviscosity. A nonlinear dynamo model with the mean field approximation is also used to examine the dynamical effect of hyperviscosity. The results suggest that great care should be taken when hyperviscosity is employed in geodynamo models.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1023336216088
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    Paper (German National Licenses)
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