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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 209 (1987), S. 154-158 
    ISSN: 1617-4623
    Keywords: Recombination ; Plasmid ; Streptomyces ; Escherichia coli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary An Escherichia coli-Streptomyces shuttle plasmid pIF132 containing two direct mel repeats was constructed. While pIF132 replicated relatively stably in E. coli (Rec+ or recA), its structure was unstable in S. lividans: recombination between the mel repeats resulted in a smaller plasmid, pIF138. Furthermore, pIF132 formed oligomers extensively in E. coli but not in S. lividans.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 208 (1987), S. 211-218 
    ISSN: 1617-4623
    Keywords: Recombination ; Mutants ; Plasmid ; Streptomyces
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Plasmid pIF132 containing two direct repeats of the mel (melanin) sequence was used to monitor intraplasmid recombination. Five mutants of Streptomyces lividans TK64 deficient in intraplasmid recombination were isolated. Four contained additional defects in aerial mycelium formation, pigmentation, and nutrient requirements; among these two showed extensive amplification of chromosomal sequences. Mutant JT46 had no pleiotropic defects but had the most severe blockage in recombination. Only one of the mutants was slightly more sensitive to UV and two were slightly more sensitive to mitomycin C. Plasmid pWCL1 (containing pIJ702, pUC12, and HBVsAg sequences; Lee et al. 1986) could not stably replicate in TK64 without spontaneous deletions. In contrast the mutant JT46 maintained the integrity of pWCL1 much more stably.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of developmental and physical disabilities 11 (1999), S. 105-114 
    ISSN: 1573-3580
    Keywords: ADHD ; cognitive inhibition ; stroop ; directed-forgetting ; mental effort
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The efficiency of cognitive inhibition was contrasted in children diagnosed with ADHD and a control group of age- and IQ-matched average children. Two tasks were used to measure inhibitory ability: the negative-prime Stroop task and a directed-forgetting memory task. Based on contemporary theoretical perspectives that postulate deficits in inhibitory function in the ADHD population, it was predicted that ADHD children would be significantly less efficient inhibitors than the average children. Contrary to predictions, however, ADHD children showed no deficits in inhibitory abilities compared to controls. Average children were faster on the second administration of the Stroop task, whereas ADHD children were slower. These results were interpreted within the framework of the inhibition models. It was proposed that differences in inhibitory abilities, such as the ones tapped here, may appear earlier than age 8, and that the engaging aspects of tasks may have optimized the ADHD children's performance. The slower performance of the ADHD group on the second administration of the Stroop task is consistent with the hypothesis that although ADHD children can inhibit, they find it more effortful to do so than do average children.
    Type of Medium: Electronic Resource
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