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  • AIDS  (1)
  • Human immunodeficiency virus  (1)
  • children's social skills  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Central nervous system Strongyloides stercoralis in acquired immunodeficiency syndrome: a report of two cases and review of the literature (1993)
    Springer
    Acta neuropathologica 86 (1993), S. 285-288 
    Details
    ISSN: 1432-0533
    Keywords: Strongyloides stercoralis ; AIDS ; Central nervous system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Hyperinfection with Strongyloides stercoralis is rare in acquired immunodeficiency syndrome (AIDS), despite endemicity in areas where infection with human immunodeficiency virus is highly prevalent. We autopsied two patients with AIDS and disseminated Strongyloides and describe their central nervous system findings. The microscopic patterns of brain infection were dissimilar in the two patients, and reflected histology in systemic viscera. In one patient, a granulomatous response accompanied filariform larvae in all locations, including granulomatous ependymitis in brain. Additionally in the brain, larvae without tissue reaction were seen. In the second patient, the absence of tissue response to larvae was body wide, and isolated parasites were found in centrum semiovale. The occurrence of these patients in a region where Strongyloides is not endemic suggests that this infection may be more prevalent in AIDS than formerly suspected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304143
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mitochondrial abnormalities in human immunodeficiency virus-associated myopathy (1995)
    Springer
    Acta neuropathologica 90 (1995), S. 366-374 
    Details
    ISSN: 1432-0533
    Keywords: Human immunodeficiency virus ; Myopathy ; Mitochondria ; Zidovudine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract There is controversy as to whether zidovudine (ZDV) induces a mitochondrial myopathy that is distinguishable from human immunodeficiency virus (HIV)-associated myopathy in ZDV-naive patients. Mitochondrial abnormalities were evaluated in skeletal muscle obtained from 18 HIV-positive, ZDV-exposed patients, and 9 who were drug naive. All patients had clinical myopathy, and underwent neuromuscular evaluation with information recorded on timing and dosage of ZDV. All underwent muscle biopsies and samples were examined without knowledge of clinical history of ZDV status. Biopsy samples were evaluated by light and electron microscopy. Mitochondrial abnormalities were seen in ZDV-treated and-naive groups, and did not correlate with ZDV exposure or cumulative ZDV dosage. Mitochondrial abnormalities displayed significant correlation with the presence and severity of myofiber degeneration on biopsy, regardless of ZDV status. As mitochondrial abnormalities reflect myofiber degeneration, present in both patient groups, they may not be used as evidence of primary mitochondrial dysfunction. The etiology of myofiber degeneration in patients with HIV infection, whether ZDV-exposed ornaive, remains unclear.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315010
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Social and solipsistic observer training: Effects on agreement with a criterion (1986)
    Springer
    Journal of psychopathology and behavioral assessment 8 (1986), S. 211-226 
    Details
    ISSN: 1573-3505
    Keywords: observer training ; observational methodology ; behavioral assessment ; observing social skills ; children's social skills ; handicapped preschoolers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Psychology
    Notes: Abstract The need to train accurate, not necessarily agreeing, observers is discussed. Intraobserver consistency as an intermediate criterion in such training is proposed and contrasted with the more familiar criterion of interobserver agreement. Videotaped observations of social interactions between handicapped and nonhandicapped preschoolers provided the medium for examining the criterion agreement of four observers trained against each type of standard. Observers generally failed to show high levels of criterion agreement whether trained to a within- or to a between-observer agreement standard. The results varied somewhat with the frequency of behaviors, however. Correlations between interobserver agreement and intraobserver consistency were variable but somewhat higher when interobserver agreement was the training criterion than when intraobserver consistency was the criterion. Correlations between interobserver agreement and criterion agreement ranged from — .16 to .89 during interobserver agreement training. Correlations between intraobserver consistency and criterion agreement ranged from — .23 to .99 during intraobserver consistency training.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00959833
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    Paper (German National Licenses)
    Fulltext
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