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  • Physics  (4)
  • AMPA-type glutamate receptor  (1)
  • nickel  (1)
  • 1
    ISSN: 1573-2932
    Keywords: recovery ; acid lake ; smelter ; copper ; nickel ; sulphate ; Rhizosolenia ; Cosmarium ; Bosmina ; Chydorus ; Chaoborus ; rotifers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Studies are reported on two small lakes at Sudbury, Ontario located close to a nickel-copper smelter which closed in 1972. At that stage, Baby Lake had a pH of 4.0–4.2 while the adjacent Alice Lake had a pH 5.9–6.3. Both lakes were almost entirely devoid of algae and had neither Zooplankton nor fish. Soon after the closure of the smelter, with its large airborne volume of sulphur dioxide and of copper and nickel containing particulates, the chemistry of the lakes began to change. By 1985, Baby Lake had changed from pH 4.0 to 6.8 and is now at pH 7.2. The pH of Alice Lake increased from a low of 5.9 in the early 1970s to 6.9–7.4 in the mid 1980s and is now at 7.3. Copper and nickel concentrations also decreased in both lakes during this period. The first biota found in the lakes in the post-smelter stage in the early 1980s were benthic red chironomids, planktonic rotifers, and a limited number of phytoplankton species, of which Rhizosolenia was the most common. By the 1990s, 13 phytoplankton species were present in each lake, with a substantial Zooplankton fauna (14 species) of rotifers, copepods, and cladocerans. There are now numerous insect larvae in the sediment and some small fish in both lakes. The biological recovery, which followed substantial reductions in acidity and in soluble nickel and copper concentrations in the waters, is a slower process than chemical recovery and is initially characterized by the dominance of a few species.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-6830
    Keywords: basal ganglia ; AMPA-type glutamate receptor ; ribosome inactivating protein ; trichosanthin ; immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract 1. To investigate the potency of a novel immunotoxin that is specific for glutamate receptor GluR1, a subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA)-type receptor channel, immunolesioning was performed. 2. A ribosome-inactivating protein, trichosanthin (TCS), was isolated and conjugated to the goat anti-rabbit IgG antibody molecule. The anti-rabbit antibody–TCS complex was preincubated with GluR1-specific rabbit antibody to produce a GluR1-specific immunotoxin. The immunotoxin was unilaterally administered into either the neostriatum or the lateral ventricle of rats. 3. Immunoreactivity for GluR1 or GluR4 was revealed in perfuse-fixed sections of the neostriatum obtained from the lesioned and control animals by immunocytochemistry. After ventricular or striatal injections of the immunotoxin, depletions of GluR1-immunoreactive neurons, the presumed GABAergic interneurons in the neostriatum, were found. Depletions of GluR4-immunoreactive perikarya, the presumed same subpopulation of striatal interneurons, were also found. In addition, no change in the pattern of distribution of immunoreactivity for GluR2 or glial fibrillary acidic protein was found in the lesioned neostriatum. These results indicate that the novel GluR1 immunotoxin is potent and specific. 4. In addition, striatal application of the immunotoxin caused a greater depletion in the number of GluR1-immunoreactive neurons. The present results also indicate that the route of immunotoxin application may be important in producing specific lesions.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-1: Polymer Chemistry 10 (1972), S. 947-953 
    ISSN: 0449-296X
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 12 (1974), S. 1559-1564 
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Four new s-triazine polymers were prepared by the mercury-induced coupling of bromodifluoromethyl-substituted ditriazinyl-perfluoroalkane derivatives. Each polymer was composed of CF3-substituted s-triazin rings alternately joined with —CF2CF2—segments and \documentclass{article}\pagestyle{empty}\begin{document}$\hbox{---}\hskip-5pt({\rm CF}_2 )_8 \hbox{---}$\end{document}, a mixture of —(CF3CFO(CF2)5OCF(CF3)— and —(CF3)CFOCF2CF(CF3)OCF2)4—, —CF2OCF2—, or —CF2SCF2—, segments. All polymers were elastomeric and displayed high temperature stability on thermogravimetric analysis. The polymers containing either —CF2OCF2— or —CF2SCF2— segments showed high temperature limits slightly lower than the other two systems.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 16 (1978), S. 483-490 
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Based on dicyclopentadiene and silacyclopentene, two linear polycycloalkylene-siloxane polymer systems have been synthesized and the thermal stability of the raw polymers evaluated by differential scanning calorimetry and thermal gravimetric analysis. The DSC data in nitrogen indicate that both polymer systems have excellent thermal stability. In air, these polymers begin to oxidize at approximately 150°C, with catastrophic oxidation occurring at about 400°C.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 17 (1979), S. 1569-1571 
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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