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  • 1
    Electronic Resource
    Electronic Resource
    Possible therapy in hereditary angioneurotic edema (HAE) (1973)
    Springer
    Journal of molecular medicine 51 (1973), S. 620-622 
    Details
    ISSN: 1432-1440
    Keywords: Hereditary angioneurotic edema ; tranexamic acid ; suramin ; C $$\bar 1$$ -inhibitor ; Hereditäres angioneurotisches Ödem ; Tranexamsäure ; Suramin ; C $$\bar 1$$ -Inhibitor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über die symptomatische Therapie des hereditären angioneurotischen Ödems mit Tranexamsäure und Suramin bei zwei Patienten berichtet. Während der erste Patient gut auf eine Therapie mit Tranexamsäure (Cyclocapron®), nicht jedoch auf Suramin ansprach, ließen sich beim zweiten Patienten die Ödemanfälle mit Suramin unterbinden.
    Notes: Summary The symptomatic therapy of hereditary angioneurotic edema with tranexamic acid and suramin in two patients is reported. The first patient responded well to tranexamic acid (Cyclocapron®) but not to suramin. In the second patient, attacks of edema could apparently be better prevented with suramin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468576
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Rhamnolipid from Pseudomonas aeruginosa inactivates mammalian tracheal ciliary axonemes (1986)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 6 (1986), S. 502-509 
    Details
    ISSN: 0886-1544
    Keywords: respiratory cilia ; dynein ; ATPase ; cystic fibrosis ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Isolated ciliary axonemes from pig trachea were exposed to increasing concentrations of purified Pseudomonas aeruginosa rhamnolipid. This is a defined ciliary system allowing observation of direct impairment of functional axonemes. Axonemal motility and ATPase activity were decreased in proportion to rhamnolipid concentrations. ATPase-associated proteins observed in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and dynein arms seen in ultrastructural cross sections progressively disappeared from axonemes with exposure to rhamnolipid. These four independent measures establish that the rhamnolipid removes the ATPase-containing outer dynein arms from the ciliary axoneme, thereby rendering the axoneme immotile.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970060509
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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