ISSN:
1432-1076
Keywords:
Key words Hyper-IgM syndrome
;
CD40 ligand
;
Necrotizing toxoplasmic encephalitis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report on a 9-year-old boy with the hyper-IgM syndrome who presented with rapid impairment of consciousness. The brain CT scan showed multiple round lucencies, and the brain histology revealed necrotizing toxoplasmic encephalitis. This patient, whose CD40/CD40 ligand system was impaired, indicates the importance of this system for defence against toxoplasmic infection. Conclusion Although disseminated toxoplasmosis is a rare complication of the hyper-IgM syndrome, it must be included in the differential diagnosis of infections.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004310050925
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