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  • Accidents  (1)
  • Isoprenaline  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of loprazolam and of triazolam on psychological functions (1984)
    Springer
    Psychopharmacology 82 (1984), S. 386-388 
    Details
    ISSN: 1432-2072
    Keywords: Loprazolam ; Triazolam ; Residual effects ; Psychological functions ; Rebound insomnia ; Accidents ; Spontaneous complaints ; Manual dexterity ; Visual analogue scales
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twelve poor sleepers of mean age 52 years performed 2 h of laboratory tests three times on 1 day during each week of nightly intake of loprazolam 0.5 mg, loprazolam 1 mg, triazolam 0.5 mg, or continued placebos. Only in the mornings did loprazolam 1 mg cause impairment in manual dexterity and card-sorting, and triazolam 0.5 mg in manual dexterity. Using difference from baseline, withdrawal of either drug after 3 weeks was associated with poorer subjective quality of sleep than following continuing placebos. The rate of spontaneous complaints (including accidents) associated with the drugs was as informative as formal testing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427691
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Debrisoquine, guanethidine, propranolol and human sleep (1971)
    Springer
    Psychopharmacology 21 (1971), S. 101-110 
    Details
    ISSN: 1432-2072
    Keywords: Sleep ; Noradrenaline ; Debrisoquine ; Overdose ; Guanethidine ; Propranolol ; β-Blockers ; Isoprenaline ; Dexamphetamine ; Imipramine ; MAOI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Debrisoquine in dosage of 20–60 mg continued for up to 10 days caused suppression of human paradoxical sleep and withdrawal rebound, and also increased intra-sleep restlessness. An overdose of debrisoquine 200 mg caused suppression of paradoxical sleep and a rebound of over 2 weeks duration. Guanethidine 20–40 mg for 21 days did not affect paradoxical sleep but increased intra-sleep restlessness and reduced stages 3 + 4 sleep. Propranolol 120 mg had no discernable effect on sleep and did not prevent actions of dexamphetamine sulphate 10 mg nor of imipramine 75 mg. The findings relate to theories of cerebral noradrenaline in the control of sleep mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572267
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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