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  • 1
    Electronic Resource
    Electronic Resource
    6-N-hydroxylaminopurine (HAP)-induced accumulation of variability in haploid and diploid strains of Aspergillus nidulans (1997)
    Springer
    Current genetics 32 (1997), S. 331-336 
    Details
    ISSN: 1432-0983
    Keywords: Key wordsAspergillus nidulans ; Accumulated variability ; 6-N-hydroxylaminopurine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Haploid and diploid strains of Aspergillus nidulans have been repeatedly treated with the strong mutagen 6-N-hydroxylaminopurine (HAP) which causes only base substitutions. An enormous amount of variability may be rapidly accumulated in haploid or diploid strains of A. nidulans. In particular, in the diploids the analysis of the results shows that after 12 cycles of treatment the conidia differ from each other for about ten recessive lethals and therefore probably for several hundreds of mutations. The viability of the heterozygous multiply mutant diploids is not appreciably different from that of untreated controls. In the diploid strains the accumulated variability was very high. The treatment of a haploid strain during vegetative growth also caused a strong accumulation of mutations, even though deleterious, because they can be maintained in the heterokaryotic condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050285
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  • 2
    Electronic Resource
    Electronic Resource
    MTDSC Calibration Dependence of the Instrumental Response Upon Experimental Conditions (1999)
    Springer
    Journal of thermal analysis and calorimetry 56 (1999), S. 699-715 
    Details
    ISSN: 1572-8943
    Keywords: calibration ; heat capacity ; MTDSC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The heat capacity calibration ‘constants’ of a commercial MTDSC system (TA 3100) were determined in a variety of experimental conditions. For a given modulation frequency, the calibration constants are the same within a few percents for different temperatures, and over a wide range of modulation amplitudes and scan rates. This variation decreases below 1% if hidden instrumental constraints are taken into account, which are related with the capability of the control system to achieve the desired temperature program. On the other hand, the calibration constant changes substantially with the period, and takes anomalously high values for the short modulation periods (20+40 s). Rules to optimize the accuracy of the system are given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1010141719713
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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