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  • 1
    Electronic Resource
    Electronic Resource
    Metastatic colon carcinoma simulating primary bile duct carcinoma via endoscopic cholangiography (1977)
    Springer
    Abdominal imaging 2 (1977), S. 75-76 
    Details
    ISSN: 1432-0509
    Keywords: Bile duct carcinoma ; Colon carcinoma ; Endoscopic retrograde cholangiopancreatography ; Adenocarcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of metastatic colon carcinoma simulating primary bile duct carcinoma is presented. The radiographic similarities via endoscopic retrograde cholangiopancreatography include bile duct narrowing and mucosal destruction. A distinguishing feature, however, is failure of the intrahepatic bile ducts to dilate in metastatic carcinoma to the biliary tree.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02256470
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Accurate Mass Measurements Using MALDI-TOF with Delayed Extraction (1997)
    Springer
    The protein journal 16 (1997), S. 363-369 
    Details
    ISSN: 1573-4943
    Keywords: Accurate mass ; MALDI-TOF ; delayed extraction ; mass spectrometry ; peptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry is now an essential tool in biopolymer analysis. Sensitivity and mass range are unsurpassed, but mass measurement accuracy and resolution have been limited. With delayed extraction and a reflecting analyzer, mass measurements using MALDI-TOF can be made with an accuracy of a few parts per million (ppm). It is possible to distinguish Lys from Gln in peptides, and to determine the elemental composition of smaller molecules (mass 100–500). In database searching strategies, a smaller mass window, resulting from an increase in mass accuracy, greatly decreases the number of possible candidates. Mass measurement accuracy with errors less than 5 ppm is demonstrated on a mixture of 12 peptides ranging in mass from ca. 900 to 3700 Da. Mass measurements on 13 peaks in an unseparated tryptic digest of myoglobin gave results with an overall average error less than 3.5 ppm, with a maximum error of 7 ppm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026376403468
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Die Schreckstoffzellen von Phoxinus phoxinus und Morulius chrysophakedion (Cyprinidae, Ostariophysi, Pisces) (1971)
    Springer
    Cell & tissue research 118 (1971), S. 203-213 
    Details
    ISSN: 1432-0878
    Keywords: Alarm substance cells ; Cyprinidae ; Epidermis ; Club cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Die Untersuchung der Histochemie und der Ultrastruktur der Schreckstoffzellen von Phoxinus phoxinus und Morulius chrysophakedion (Cyprininae, Cyprinidae, Cypriniformes, Ostariophysi) führte zu übereinstimmenden Ergebnissen. Unmittelbar perinucleär sind Ribosomen, Mitochondrien und ein Golgikomplex nachweisbar, von dem ein Netzwerk tubulärer Systeme ausgeht. Histochemisch sind in unmittelbarer Kernnähe gelegentlich Glykogengranula, stets ein deutlicher RNS-Gehalt und die Aktivitäten der Succinatdehydrogenase, der Lactatdehydrogenase, in einigen Zellen der Glucose-6-phosphat-dehydrogenase darstellbar. Im gesamten Cytoplasma der Schreckstoffzelle ist die Aktivität der Leucinaminopeptidase vorhanden, deren Maximum ebenfalls in Kernnähe vorliegt. Nur im kernfernen Cytoplasma wurden Proteine und diastaseresistente Polysaccharide nachgewiesen. Aus den Ergebnissen geht hervor, daß die Schreckstoffzellen sekretorisch tätig sind; vermutlich handelt es sich bei dem spezifischen Sekret um ein kleinmolekulares Protein.
    Notes: Summary The histochemical studies of the alarm substance cells from Phoxinus phoxinus and Morulius chrysophakedion (Cyprininae, Cyprinidae, Cypriniformes, Ostariophysi) are in total agreement with the results of the ultrastructural investigations. Perinuclear ribosomes, mitochondria, and a golgi complex are demonstrated. A tubular network radiates from the golgi complex. Histochemically, glycogen granula can occasionally be demonstrated in proximity to the nucleus. Consistently a strong RNA reaction as well as succinic-dehydrogenase activity, lactic-dehydrogenase activity, and in some cells glucose-6-phosphatedehydrogenase activity can be shown. In the cytoplasm of the alarm substance cell leucyl-aminopeptidase activity exists; its maximum lies in vicinity of the nucleus. Proteins and diastase-resistant polysaccharides are found only in cytoplasm not directly adjacent to the nucleus. The results indicate that the alarm substance cells show a secretory activity. It is assumed that the specific secrete is a protein of low molecular weight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341564
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Epidermale Organe am Kopf von Morulius chrysophakedion (Cyprinidae, Ostariophysi, Pisces) (1970)
    Springer
    Cell & tissue research 103 (1970), S. 218-231 
    Details
    ISSN: 1432-0878
    Keywords: Fishes ; Morulius chrysophakedion ; Epidermis ; Flask-shaped organs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Im Kopfbereich von Morulius chrysophakedion liegen epidermale Organe in Gruppen beisammen. Im Gegensatz zu den oberflächlichen Perlorganen anderer Cyprinidae handelt es sich hierbei um voluminöse Einsenkungen der Epidermis in das darunter gelegene Bindegewebe, von dem aus gefäßführende Papillen in das Organinnere hineinziehen. Elektronenmikroskopische und histochemische Befunde sprechen für eine relativ hohe Stoffwechselaktivität der das Organ aufbauenden Polsterzellen, als deren Ergebnis eine Art Verhornung an der Organspitze vorliegt. Hinweise auf eine Funktion der epidermalen Organe von Morulius als Sinnesorgane wurden nicht gefunden; sie müssen daher von den Fahrenholzschen Organen der Dipnoi und Brachiopterygii unterschieden werden.
    Notes: Summary There are groups of epidermal organs in the head region of Morulius chrysophakedion. In contrast to the superficial perlorgans of some other Cyprinidae these organs are formed by an infolding of epidermis into the connective tissue beneath. From this tissue vessels reach into the interior of the organ. Electron microscopical and histochemical data give evidence of a relatively high metabolic activity in the “Polsterzellen” from which the organ is built up. These cells give rise to a keratinized area at the top of the organ. There is no evidence that the epidermal organ has the function of a sense organ as in the organs of Fahrenholz in Dipnoi and Brachiopterygii.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00337313
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    Paper (German National Licenses)
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