ISSN:
1420-9071
Keywords:
Acetaldehyde oxydation
;
alcohol dehydrogenase
;
aldehyde dehydrogenase
;
Drosophila melanogaster
;
Drosophila simulans
;
ethanol catabolism
;
null-mutants for alcohol dehydrogenase
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Aldehyde dehydrogenase (ALDH) activity is demonstrated in four strains ofD. melanogaster lacking active alcohol dehydrogenase (ADH-null mutants). In the four strains, ALDH activities are similar to those found in a wild strain. It is concluded that ADH-null flies are able to detoxify acetaldehyde. This finding is discussed in relation with the dual function of ADH proposed recently.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01970027
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