ISSN:
0942-0940
Keywords:
Acoustic neurilemomas
;
cell kinetics
;
labelling index
;
monoclonal antibody MIB 1
;
proliferative activity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Microscopic sections obtained from paraffin blocks of 30 consecutive neurilemomas stored in 1989 were investigated immunohistochemically with the new monoclonal antibody MIB 1 directed against recombinant parts of Ki-67 antigen. The immunohistochemical staining was carried out on dewaxed microwave-oven-processed paraffin sections of formalin-fixed tumour tissues. The labelling index (LI) obtained was below 1% in 21 cases, 1–3% in 7 cases and more than 3% in 2 cases. There was no correlation between the LI and the age of the patients or the tumour size. The major advantage of MIB 1 over previous immunohistochemical methods is its usefullness in long preserved sections which are ideal for retrospective studies.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01428499
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