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  • 1
    Electronic Resource
    Electronic Resource
    Does haloperidol block methylphenidate? (1996)
    Springer
    Psychopharmacology 126 (1996), S. 70-74 
    Details
    ISSN: 1432-2072
    Keywords: ADHD ; Motivation ; Attention ; Activation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effect of methylphenidate preceded by a moderate dose of haloperidol on reaction times over the duration of a continuous performance test (CPT) was investigated in ten male children, with a DSM-III diagnosis of attention deficit disorder with hyperactivity disorder (ADDH). Using a within-subject double-blind design, the effects of methylphenidate preceded by haloperidol on reaction time during the first and second blocks of CPT test were compared. Methylphenidate maintained a significantly improved reaction time in the second block of the CPT test. When methylphenidate, preceded by placebo, was preceded by haloperidol this effect was not observed, suggesting opposing effects on attentional systems by methylphenidate versus haloperidol. The study is the first to examine the “blocking” effect of haloperidol over the course of a CPT. The results suggest that dopamine systems are involved in the maintenance of the CPT response, and support an “incentive motivation” theory of sustained attention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02246413
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of a Gaussian-modified dispersion model for atmospheric release from the Marcoule nuclear site (2000)
    Springer
    Environmental modeling and assessment 5 (2000), S. 75-81 
    Details
    ISSN: 1573-2967
    Keywords: modified Gaussian model ; in situ measurements ; model evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This paper presents a mathematical model of local pollutant dispersion designed to compute the concentration field above and around the Marcoule nuclear site. The model is based on integrating the classical turbulent diffusion equation, corrected (prior to integration) by experimental wind tunnel data obtained for a scaled-down model of the site. The computed results are compared with full-scale experimental observations at Marcoule in the case of neutral atmosphere. A comparison with the standard Gaussian model is also made. Finally, a critical analysis of the model is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1019001409408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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