ISSN:
1432-1440
Keywords:
Herpes simplex virus
;
Acyclovir resistance
;
Foscarnet
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The case of a 25-year-old homosexual man with large inguinal and perianal ulcers is reported. He had been pretreated extensively with acyclovir. Herpes simplex virus (HSV) was identified in the ulcer tissue byin-situ hybridization. No clinical improvement with acyclovir but a prompt response to foscarnet was noted. In a relapse after 11 weeks an acyclovir-resistant HSV type 2 was isolated. Again, a prompt response to foscarnet was noted. The case is presented in detail, and the clinical impact of resistance of HSV to acyclovir is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01666854
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