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  • Adenomyosis  (1)
  • Early and late changes  (1)
  • 1
    ISSN: 1432-1084
    Keywords: Cerebral irradiation ; Early and late changes ; rCBF ; SPECT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a prospective study of changes in regional cerebral blood flow (rCBF) using HMPAO-SPECT during and after brain irradiation. 54 patients were compared to a base line study before irradiation. Follow up studies were performed in 49 patients. An increase in rCBF during irradiation was found in 36 patients, 5 of whom normalised at the end of radiation therapy. The other 20 patients normalised within 6 months. A total of 8 patients had a decrease in rCBF during irradiation, 4 patients returning to pre-irradiation levels 0–1 month after therapy. Five patients showed no immediate changes in rCBF. Late changes have not yet been seen and are only discussed in patients examined due to neurological symptoms apparent 2 years after therapy. Further follow up is required in this ongoing study.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-808X
    Keywords: Schlüsselwörter Archimetra ; Endometriose ; Adenomyose ; Uterus ; Samentransport ; Key words Archimetra ; Endometriosis ; Adenomyosis ; Uterus ; Sperm transport
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The human uterus is composed of the paramesonephric archimetra and the non-paramesonephric neometra. The archimetra consists of the glandular as well as stromal part of the endometrium and the subendometrial myometrium and meets several fundamental functions in the early process of reproduction such as providing the site of implantation, uterine directed sperm transport and high fundal implantation of the embryo by uterine peristalsis as well as inflammatory defence. The neometra is composed of the stratum vasculare and stratum supravasculare. Its main function is to provide the forces for expulsion of the fetus. Endometriosis is considered a disease of the archimetra in that it constitutes a non-obilgatory consequence of uterine adenomyosis or its early manuifestations. This view is supported by several lines of evidence. First: The eutopic endometrium shows alterations similar to those seen in endometriotic lesions that are not found in the endometrium of women free of disease. Second: Uteri of women with endometriosis display hyper- and dysperistalsis of which the extent does not correlate with the severity of the disease. This dysfunction results in a break down of rapid and sustained directed sperm transport and may explain sterility and subfertility in women with mild-to-moderate endometriosis. Third: In women with endometriosis there is a proliferative and infiltrative expansion of all elements of the archimetra into the outer myometrial layers. There is no correlation of the extent of the infiltrative expansion with the grade of endometriosis but with the age of the patients. In MR imaging these findings are similar or identical with those found in adenomyosis.
    Notes: Zusammenfassung Der menschliche Uterus setzt sich aus einer inneren paramesonephrischen Archimetra und einer äußeren nicht-paramesonephrischen Neometra zusammen. Die Archimetra besteht aus dem Endometrium und dem Stratum subvasculare des Myometrium und erfüllt verschiedene vom Ovar gesteuerte Funktionen im frühen Prozeß der Reproduktion wie Aufbau des Endometriums für die Implantation, uterine Peristaltik für den gerichteten Spermientransport und die hohe fundale Implantation sowie die Infektabwehr. Die Neometra besteht aus den beiden äußeren Muskelschichten, dem Stratum vasculare und supravasculare. Die wesentliche Funktion besteht im Aufbringen der Kräfte für die Geburt. Die Endometriose wird als Folge einer Adenomyosis oder deren Frühmanifestationen und somit als eine Erkrankung der Archimetra angesehen. Dieses Konzept stützt sich auf spezifische Veränderungen des eutopen Endometriums bei Frauen mit Endometriose, auf archimetrale Funktionsstörungen wie Hyper- und Dysperistaltik sowie auf eine archimetrale Infiltration in das darunter liegende Myometrium mit dem Bild einer Adenomyosis uteri.
    Type of Medium: Electronic Resource
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