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  • Analytical Chemistry and Spectroscopy  (12)
  • Organic Chemistry  (3)
  • Adhesions  (2)
  • 1
    ISSN: 1530-0358
    Keywords: Adhesions ; Complications ; Small-bowel obstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: The study contained herein was undertaken to establish the incidence of small-bowel obstruction, adhesiolysis for obstruction, and additional abdominal surgery after open colorectal and general surgery. METHODS: A retrospective cohort study was performed using patient-specific Health Care Financing Administration data to evaluate a random 5 percent sample of all Medicare patients who underwent surgery in 1993. Of these, 18,912 patients had an index abdominal procedure. Two-year follow-up data documented outcomes of hospitalizations with obstruction, adhesiolysis for obstruction, and/or additional open colorectal or general surgery. RESULTS: Within two years of incision, excision, and anastomosis of intestine (International Classification of Diseases (ICD)-9 code 45), 14.3 percent of patients had obstructions, 2.6 percent required adhesiolysis for obstructions, and 12.9 percent underwent additional open colorectal or general surgery. After other operations of intestine (ICD code 46), 17 percent of patients had obstructions, 3.1 percent required adhesiolysis for obstructions, and 20.2 percent underwent additional open colorectal or general surgery. After operations of rectum, rectosigmoid, and perirectal tissue (ICD code 48), 15.3 percent of patients had obstructions, 5.1 percent required adhesiolysis for obstructions, and 16.4 percent underwent additional open colorectal or general surgery. After other operations on the abdominal region (ICD code 54), 12.4 percent of patients had obstructions, 2.3 percent required adhesiolysis for obstructions, and 8.8 percent underwent additional open colorectal or general surgery. CONCLUSIONS: In this retrospective study of Medicare patients, we learned that bowel obstruction, adhesiolysis for obstructions, and additional abdominal surgery occurred more often after abdominal surgery than was previously published.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 43 (2000), S. 1749-1753 
    ISSN: 1530-0358
    Keywords: Adhesions ; Operative technique ; Complications ; Economics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: The purpose of this study was to document prospectively the time required to gain access to the abdomen to perform a planned procedure in patients with and without previous surgery. METHODS: Patients were obtained from the consecutive cases of 11 surgeons at three colorectal surgery centers. Opening time (skin incision to retractor placement) was measured and recorded in the operating room by the circulating nurse or by an independent researcher. Demographic data including the number and type of previous operations and the presence and severity of adhesions were recorded by the staff surgeon. A comparison of opening times between patients with and without previous abdominal operations was conducted. RESULTS: One hundred ninety-eight patients had abdominal operations. Fifty-five percent had previous abdominal procedures. Patients with prior surgery required a mean of 21 minutes to open their abdomens, whereas patients without prior surgery required a mean of 6 minutes (P〈0.01). The median times were 17 and 6 minutes, respectively. Eighty-three percent of patients with prior surgery had adhesions, whereas only 7 percent of patients had adhesions on their initial operation. Patients with prior surgery also had higher grade adhesions (P〈0.001). Irrespective of previous surgery, comparing patients with adhesions with those without, patients with adhesions required a mean of 22 minutes to open, whereas the lack of adhesions resulted in a mean opening time of 6 minutes. CONCLUSIONS: Previous surgery and the presence of adhesions add significant time to opening the abdomen.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The solid-state CP/MAS 13C-NMR spectra (cross-polarization/magic-angle spinning 13C-NMR) of eight lower cyclic and one linear oligomers and several polymers of (R)-3-hydroxybutanoic acid (3-HB) are reported. The polymeric samples of different origin and molecular weight give remarkably similar and well resolved spectra, indicating considerable similarity in the conformations of the molecules and homegeneity in the solid-state environment. The crystalline cyclic oligomers 1-8 containing 3-9 units of 3-HB give very well resolved spectra. The number of nonequivalent positions in the solid state can be identified and is in accord with structures from X-ray diffraction where these were determined. The spectra of the oligolides become increasingly similar to those of the polymer as the ring size increases. This spectral evidence supports the view of a homogeneous and well defined conformation for the polymeric material (as proposed previously, based on other experiments).
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 716 (1968), S. 29-36 
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Stannyl-alkine reagieren mit Phenylisocyanat überraschenderweise zu 5-Alkylidenhydantoinen 3, mit Diphenyl-tetrazin in einer Diels-Alder-Reaktion zu Pyridazinen 6, mit Jod zu Jod-alkinen; Carbonsäure-chloride führen zu Alkinyl-ketonen, polarisierte Carbonyl-Verbindungen analog einer Grignard-Reaktion zu substituierten Propargylalkoholen.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 716 (1968), S. 19-28 
    ISSN: 0075-4617
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Stannylierte Alkine RnSn(C = C - R′)4-n mit n = 0, 2, 3 (Tabb. 2, 3) werden einfach und schonend dargestellt durch azeotropen Wasser-Entzug aus dem freien Alkin und Dialkyl(bzw. -aryl)-zinnoxid oder Trialkyl(bzw. -aryl)-zinnoxid. Der Rest R′ kann funktionelle Gruppen tragen, z.B. OCH3, CONH2, CO2CH3 und CN. Das Verfahren ist auch auf Pb- und Hg-Alkin-Verbindungen anwendbar. Der Mechanismus von Knüpfung und Hydrolyse der C≡C-Sn-Gruppe wird untersucht. Sowohl aus vergleichenden IR-Studien wie aus Valence-Bond-Berechnungen (VB + CI-Methode) folgt, daß am Bindungssystem eine Struktur C≡C-Sn beteiligt ist.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The 300 MHz 1H NMR spectrum of 4-vinylbutyrolactone has been recorded and analysed. The results showed that the compound is a mixture of two rapidly interconverting envelope forms in which (C-3) is the flap atom. The vinyl group favours the pseudo-equatorial orientation by 1·9 ± 0.3 kJ mol-1, as shown by the dependence of the vicinal coupling constants on temperature.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 14 (1980), S. 324-326 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The nitrogen inversion barriers of nine 3,6-dihydro-1,2-oxazines are discussed. Polar solvents were found to increase the nitrogen inversion barriers which, in turn, decrease with increasing size of the N-substituent.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 33 (1995), S. 600-602 
    ISSN: 0749-1581
    Keywords: NMR ; 13C NMR ; Tetrahydro-1, 3-oxazines ; ring chain tautomerism, solid-state NMR ; kinetics ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Condensation of cis-2-aminomethylcyclohexanol with p-nitrobenzaldehyde under mild conditions initially gives the imine as the kinetically controlled product. The imine undergoes a solid-state rearrangement to the bicyclic tetrahydro-1, 3-oxazine. The kinetics of the rearrangement were followed by solid-state CP/MAS 13C NMR spectroscopy over the temperature range 283-297 K and the reaction was shown to have an activation energy of 85.0 ± 14.7 kJ mol-1. The probable reaction mechanism is discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 33 (1995), S. 841-843 
    ISSN: 0749-1581
    Keywords: NMR ; solid-state NMR ; CP/MAS NMR ; dynamic NMR ; phenyl rotation ; trimethylammonium rotation ; methyl rotation ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 13C CP/MAS NMR spectra of trimethyl(3-phenylpropyl)ammonium bromide show evidence of three independent rotational processes in the solid: methyl rotation, trimethylammonium rotation and phenyl rotation.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 30 (1992), S. 1070-1074 
    ISSN: 0749-1581
    Keywords: Bicyclo[3.3.1]nonan-9-one derivatives ; CP/MAS NMR spectra ; Chair/chair-chair/boat equilibrium ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Several derivatives of bicyclo [3.3.1]nonan-9-one were examined by CP/MAS NMR spectroscopy in the solid state. Contrary to an earlier report based on X-ray crystallography, no conclusive evidence was found for the existence of a chair/chair-chair/boat equilibrium in the temperature range -100 to +20 °C. It is concluded that if such solidstate equilibria exist they have free energies of activation for ring inversion in the solid of less than 31 kJ mol-1.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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