Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 418 (1991), S. 144-152 
    ISSN: 1432-2013
    Keywords: Patch clamp ; Bufo marinus ; Dihydropyridine ; Bay K 8644
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Single-channel currents were recorded from two classes of Ca2+ channels in visceral smooth muscle cells isolated from the stomach of the toad, Bufo marinus: a class of small-conductance channels (approximately 11 pS) and a class of large-conductance channels (approximately 26 pS). Small-conductance channels were present in a majority of patches and gave rise to a slowly inactivating current (t1/2 ≈ 250 ms at 0 mV). Openings of large-conductance channels could be unequivocally resolved only in the presence of the dihydropyridine Ca2+ agonist Bay K 8644. Two subtypes of the large-conductance channels were found — those with a very slow rate of decay (〉 500 ms) and those with a faster one (〈 100ms). Large-conductance channels resemble L-type Ca2+ channels of other preparations. Small-conductance channels do not fit unambiguously into the other existing categories (i.e., N or T). Correspondence between single-channel and macroscopic Ca2+ currents is discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 64 (1992), S. 395-401 
    ISSN: 1439-6327
    Keywords: Cold stress ; Cooling rate ; Intramuscular temperature ; Tissue temperature ; Transient response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The transient temperature response of the resting human forearm immersed in water at temperatures (T w) ranging from 15 to 36°C was investigated. Tissue temperature (T t) was continuously monitored by a calibrated multicouple probe during the 3-h immersions.T t was measured every 5 mm, from the longitudinal axis of the forearm to the skin surface. Skin temperature, rectal temperature, and blood flow ( $$\dot Q$$ ) were also measured during the immersions. The maximum rate of change of the forearm mean tissue temperature ( $$\dot T_{{\text{t, max}}}$$ ) occurred during the first 5 min of the immersion. $$\dot T_{{\text{t, max}}}$$ was linearly dependent onT w (P〈0.001), with mean values (SEM) ranging from −0.8 (0.1) °C · min−1 at 15°C to 0.2 (0.1) °C · min−1 at 36°C. The maximum rate of change of compartment mean temperature was dependent (P〈0.001) on the radial distance from the longitudinal axis of the forearm. The half-time for thermal steady state of the forearm mean tissue temperature was linearly dependent onT w between 30 and 36°C (P〈0.01), with mean values (SEM) ranging from 15.6 (0.6) min at 30°C to 9.7 (1.2) min at 36°C and not different between 15 and 30°C, averaging 16.2 (0.6) min. There was a significant linear relationship between the half-time for thermal steady-state of the compartment mean temperature and the radial distance from the longitudinal axis of the forearm for each value ofT w tested (P〈0.001). The data of the present study suggest that the forearm $$\dot Q$$ is an important determinant of the transient thermal response of the forearm tissue during thermal stress.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 82 (2000), S. 24-29 
    ISSN: 1439-6327
    Keywords: Key words Accidental immersion ; Adiposity ; Aerobic capacity ; Cooling rate ; Rectal temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The influence of body adiposity, arm skinfold thickness, aerobic capacity, and cooling rate were studied in a mock survival swimming situation conducted in water at around 14 °C. Seventeen adult participants wore personal floatation devices on top of seasonal clothing and were asked to swim as far as they could, as if attempting to reach shore following an accidental immersion in cold water. Triceps and patellar skinfold thickness showed a significant correlation with distance covered (r=0.70 and 0.56, respectively), while abdominal skinfold and percent body fat showed no significant correlation. Maximum oxygen consumption (V˙O2max) was not significantly related to distance covered. There was a negative correlation between body cooling rate during the swimming period and distance covered. A multiple stepwise regression analysis, however, indicated that the only significant contributor to variance in the distance covered was the triceps skinfold thickness (r 2=0.49). It was concluded that for a healthy subject accidentally immersed in cold water, triceps skinfold thickness is a stronger predictor of the swimming distance covered than body adiposity, V˙O2max, or the drop in core temperature.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 63 (1991), S. 188-193 
    ISSN: 1439-6327
    Keywords: Cold-induced vasodilatation ; Cold stress ; Tissue heat loss ; Tissue temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of the present study was to investigate the intramuscular temperature fluctuations in the human forearm immersed in water at 15°C. Tissue temperature (T t) was continuously monitored by a calibrated multi-couple probe during 3 h immersion of the forearm. The probe was implanted approximately 90 mm distal from the olecranon process along the ulnar ridge. T t was measured every 5 mm, from the longitudinal axis of the forearm (determined from computed tomography scanning) to the skin surface. Along with T t, rectal temperature, skin temperature and heat loss of the forearm were measured during the immersions. Five of the six subjects tested showed evidence of cyclic temperature fluctuations in the forearm limited to the muscle tissue. The first increase of the muscle temperature was observed 75 (SE 6) min after the onset of the immersion, and the duration of the cycle averaged 36 (SE 3) min. The maximum increase of the muscle temperature, which ranged between 0.4°C and 1.0°C, was measured at the axis of the forearm, and was inversely correlated to the circumference of the subject's forearm (P〈 0.05). No corresponding increases of the skin temperature and heat loss of the forearm were observed for the complete duration of the immersion. These data support the hypothesis of a significant contribution of the muscle vessels during cold-induced vasodilatation in the forearm.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...