Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 44 (1995), S. 548-555 
    ISSN: 1420-908X
    Keywords: Meloxicam ; Piroxicam ; Diclofenac ; Adjuvant arthritis ; Lewis rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of meloxicam, piroxicam, diclofenac and tenidap on the swelling of hind paws, radiologically-detectable bone and cartilage destruction of hind paws, increase in spleen weight, increase in erythrocyte sedimentation rate and changes in serum protein composition in male Lewis rats with adjuvant arthritis were studied following once-daily oral administration of these drugs for 21 days. All the drugs dose-dependently inhibited hind paw swelling. For equal activity against hind paw swelling caused by the secondary reaction, the required daily dose of piroxicam was about twice that of meloxicam; those of diclofenac and tenidap were about 3.5 and 60 times higher respectively. The bone and cartilage destruction induced by adjuvant arthritis were inhibited by meloxicam at low daily doses and by piroxicam at doses approximately four times those of meloxicam. Diclofenac and tenidap had only a weak effect on radiologically-detectable lesions when administered at doses sufficient to reduce paw swelling. Meloxicam also had a dose-dependent corrective effect on the systemic changes which occur in adjuvant arthritic rats, e.g. increase in spleen weight, increase in erythrocyte sedimentation rate and changes in serum protein composition. Piroxicam produced similar effects, at 3–4 times higher doses. Diclofenac and tenidap did not show comparable effects when administered at appropriate doses. These findings indicate that the action of meloxicam and piroxicam differs from that of diclofenac and tenidap in adjuvant arthritis in the Lewis rat. At oral doses which significantly reduce edema formation, only meloxicam and piroxicam showed a significant effect on systemic parameters of adjuvant disease in the Lewis rat.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 361 (1983), S. 893-893 
    ISSN: 1435-2451
    Keywords: Emergency doctor ; Time lapse ; Primary diagnosis ; Effectiveness ; Notarzt ; Alarmierungszeiten ; Erstdiagnose ; Effektivität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Wechsel zwischen realistischen Aufnahmen am Unfallort und grafischen Darstellungen statistischer und medizinischer Erhebungen wird aus Anlaß des 25jährigen Bestehens des Kölner Notarztdien stes anhand von etwa 80000 Einsätzen die Organisation, Indikation und Effektivität des Notartzeinsatzes dargestellt und über häufige Maßnahmen bei der Versorgung des chirurgischen Notfallpatienten berichtet. 97 aller Einsatzorte ließen sich innerhalb von 10 min erreichen. Die Qualität der ersten Diagnose am Unfallort läßt sich ebenso belegen wie die größere Überlebenschance von Schwerverletzten, die am Unfallort ärztlich versorgt werden.
    Notes: Summary Presented in a lively sequence of realistic pictures of emergency situations and graphic tables about statistic and medical facts, a review is given of 80000 emergency cases within the 25 years of existence of the Cologne Emergency-Doctor Service. The organization, indication and effectiveness of this special task force are pointed out, and common measures of medical help for adequate care of injured patients are shown. Of all locations with emergency cases, 97 % were reached within 10 min. The quality of primary diagnosis at the place of the accident is shown clearly as is the higher chance for survival of polytraumatized patients in the hands of emergency doctors at the place of accident.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...