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  • Gastroesophageal reflux  (3)
  • Adriamycin  (1)
  • Biocide  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 12 (1997), S. 552-555 
    ISSN: 1437-9813
    Keywords: Electrogastrography ; Gastroesophageal reflux ; Esophageal atresia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Surface electrogastrography was performed in 18 patients with esophageal atresia (EA) and 10 normal controls to investigate the possible role of a congenital enteric nerve defect as a cause of gastroesophageal reflux (GER), which is common after repair of EA. The means of the dominant frequencies and ranges of the frequency distribution were compared. The dominant frequencies (0.047+/-0.007 Hz) in the EA group did not differ significantly from those of the controls (0.050±0.007 Hz,P 〉0.1), although 2 patients had bradygastria and 2 had tachygastria in the EA group. The range of the frequency distribution was significantly wider in the EA group compared with normal children (P = 0.002). The wide frequency distribution in children with EA suggests disturbed electrical activity of the stomach, which could be associated with poor electromechanical coupling and, hence abnormal gastric contraction.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-9813
    Keywords: Key words Esophageal atresia ; Gastroesophageal reflux ; Adriamycin ; Fetal rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gastroesophageal reflux is common in children after successful repair of esophageal atresia (EA), and may be related to a congenital neuronal abnormality of the esophagus. This study employed a fetal rat model of adriamycin-induced EA to investigate whether the innervation of the esophagus is abnormal in EA. The fetal rats were divided into four groups: (1) normal controls; (2) a saline-injected controls; (3) adriamycin administered but without the development of EA; and (4) adriamycin-induced EA. The distal esophageal segments were immunostained with a general neural marker, protein gene product 9.5 (PGP). Immunoreactivity per cross-sectional area (/xsa) was measured with an image analyzer. The extent of the esophageal circumference encircled by PGP-stained nerve tissue was assessed. While there was no significant difference in PGP immunoreactivity/xsa between the groups, the near-complete ring of nerve tissue along the plane of the myenteric plexus was replaced by clusters of nerve tissue in the atretic group (normal vs EA, P = 0.001, Mann-Whitney U test). The abnormal distribution of nerve tissue in the atretic esophagus may be contributing factor in the esophageal dysmotility seen in EA.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric surgery international 12 (1997), S. 552-555 
    ISSN: 1437-9813
    Keywords: Key words Electrogastrography ; Gastroesophageal reflux ; Esophageal atresia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Surface electrogastrography was performed in 18 patients with esophageal atresia (EA) and 10 normal controls to investigate the possible role of a congenital enteric nerve defect as a cause of gastroesophageal reflux (GER), which is common after repair of EA. The means of the dominant frequencies and ranges of the frequency distribution were compared. The dominant frequencies (0.047+/–0.007 Hz) in the EA group did not differ significantly from those of the controls (0.050+/–0.007 Hz, P 〉0.1), although 2 patients had bradygastria and 2 had tachygastria in the EA group. The range of the frequency distribution was significantly wider in the EA group compared with normal children (P = 0.002). The wide frequency distribution in children with EA suggests disturbed electrical activity of the stomach, which could be associated with poor electromechanical coupling and, hence abnormal gastric contraction.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    ISSN: 1432-0789
    Keywords: Earthworm ; Enchytraeid ; Tillage ; Organic matter ; Biocide ; Agroecosystems
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Earthworm and enchytraeid densities and biomass were sampled over an 18-month period in conventional and no-tillage agroecosystems. Overall, earthworm densities and biomass in the no-till system were 70% greater than under conventional tilling, and enchytraeid densities and biomass in the no-till system were 50%–60% greater. To assess the role of annelids in the breakdown of soil organic matter, carbofuran was applied to field enclosures and target (earthworm and enchytraeid biomass, standing stocks of organic matter) and non-target effects (bacteria, fungi, protozoa, nematode and microarthropod densities, litter decay rates, plant biomass) were determined in two 10-month studies. In the winter-fall study, carbofuran reduced the annelid biomass, and total soil organic matter standing stocks were 47% greater under no-till with carbofuran compared to control enclosures. Twelve percent of the difference could have been due to non-target effects of carbofuran, as determined from litterbag decay rates. In the summer-spring study, carbofuran again significantly reduced the annelid biomass, and treated pens in the no-till area had significantly greater standing stocks of fine organic matter (43%–45%). Although the densities of bacteria and nematodes were reduced in carbofuran-treated litterbags under a no-till system, the rates of decay were not reduced and estimates of the amount of organic matter processed could not be adjusted for non-target effects. A 76% difference in the standing stock of coarse organic matter between control and carbofuran-treated pens in the conventional-till system indicated further non-target effects. We concluded that our estimates of the amount of organic matter processed by annelids in no-till and conventionally tilled agroecosystems represented a maximum potential because of the confounding non-target effects of carbofuran.
    Type of Medium: Electronic Resource
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