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  • 1
    Electronic Resource
    Electronic Resource
    Between and within subject variation of the first phase insulin response to intravenous glucose (1988)
    Springer
    Diabetologia 31 (1988), S. 123-125 
    Details
    ISSN: 1432-0428
    Keywords: Variability ; insulin ; glucose
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Eight normal subjects underwent two intravenous glucose tolerance tests to determine the between and within subject variation of the first phase insulin response. Variability was represented by the coefficient of variation. The between subject variation for the incremental 0–10 min insulin area was 58%, and the within subject variation was 22% (median value), range 3–55%. The variation of the first phase response expressed in four different ways was compared. The total and incremental (above fasting levels) 0–10 min areas provided less variable results (variation 52 and 58%) than the 1+3 min insulin levels (variation 72%) or mean of the incremental 3–5 min insulin levels (variation 66%). The ratio of the incremental 0–10 min insulin to glucose areas was as variable (variation 53%) as the insulin responses alone. The variability of insulin responses to intravenous glucose severely limits their value as early predictors of B-cell failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395560
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phenylketonuria: treatment in adolescence and adult life (1996)
    Springer
    European journal of pediatrics 155 (1996), S. S93 
    Details
    ISSN: 1432-1076
    Keywords: Key words Phenylketonuria ; Adult ; dietary treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In our clinic the decision on whether to continue with dietary treatment of phenylketonuria or not is left to each adolescent and adult patient after the advantages and disadvantages, as discussed in this paper, of continuing diet have been presented to them. As a result 61 of 132 patients have stopped diet or declined to restart and only 4 of them have phenylalanine values below 1000 μmol/l. Seventy-one patients have remained on diet or started again with phenylalanine values below 1000 μmol/l in 58 of them. This series of 132 excludes women who returned to diet to conceive.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00014261
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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