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  • Aggression  (1)
  • Dimethyltryptamine  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 40 (1974), S. 211-223 
    ISSN: 1432-2072
    Keywords: Hallucinogens ; Hallucinations ; LSD ; Dimethyltryptamine ; Chlorpromazine ; Amphetamine ; Monkey Behavior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An attempt was made to develop an objective behavioral profile that could be used to distinguish the behavioral effects of hallucinogens from those of other classes of drugs. Saline, bromo-lysergic acid diethylamide, and two doses each of lysergic acid diethylamide (LSD), diemethyltryptamine (DMT), chlorpromazine, and d-amphetamine sulphate were administered to solitary adolescent rhesus monkeys whose behavior was observed, videotaped, and scored in a number of categories. Hallucinogens (LSD and DMT) could be distinguished from other drugs by the increased frequency of unusual behaviors such as spasms, stereotypy, and inappropriate behavior, and the decreased amount of exploration time. Hallucinogens also produced distinctive qualitative changes in behavior.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Morphine ; Naloxone ; Dependence ; Aggression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Weight loss and shock-elicited aggression have been compared as quantitative indices of morphine abstinence in rats. A range of doses of morphine was administered to rats by i.p. injection twice daily for 12–15 days. After injections were stopped, morphine-abstinent rats lost weight precipitously, and showed an increased frequency of fighting in response to aversive stimulation (foot-shock). Recovery of weight appeared complete after 15–20 days but a significant increase in aggression was found at 18 days post-withdrawal; this virtually disappeared after 52 days. Both the amount of weight lost and the frequency of fighting increased as a function of the previous maintenance dose of morphine; the effective dose range appeared similar for these two indices. Weight loss was much less variable than fighting, had the advantage of rapid, objective measurement, and appeared to be the more reliable index of abstinence.
    Type of Medium: Electronic Resource
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