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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 66 (1992), S. 149-158 
    ISSN: 0047-6374
    Keywords: Adherence ; Aging ; Collagen ; Fibronectin ; Macrophages
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1750
    Keywords: Aging ; Glutathione ; Bronchoalveolar lavage (BAL)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the influence of age on glutathione (GSH) content in the distal lung and the lung tissue of mice. From 1 to 28 months of age, the quantity of GSH and glutathione disulfide (GSSG) in bronchoalveolar lavage (BAL) fluid and in the lung tissue were determined. The GSH content in BAL fluid, which reflects the antioxidant screen of the distal lung, decreased with advancing age. The ratio of GSSG to GSH increased in later life, suggesting increase of oxidation of the epithelial lining fluid in old mice. The GSH content in the lung tissue also decreased with aging. Therefore the lower respiratory tract may be less able to defend against external attack, including attack by oxygen-derived active molecules, in senescent mice. The decrease of the antioxidant screen of the distal lung may be associated with impaired lung defense in relation to oxidant-antioxidant balance in aged mice.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 26 (1988), S. 641-646 
    ISSN: 1741-0444
    Keywords: Admittance plethysmography ; Arterial compliance ; Human limb ; Noninvasive measurement ; Volume elastic modulus ; Volume oscillometric method
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Arterial elasticity expressed by such indices as volume elastic modulus Ev and compliance Ca were noninvasively measured in various human limb segments; the upper arms, forearms, fingers, thighs, calves and toes. These indices are defined, respectively, as $$E_v = \Delta P/(\Delta V/\bar V_a )$$ and Ca=ΔV/ΔP, where ΔP is pulse pressure, $$\bar V_a $$ mean arterial volume and ΔV its pulsatile variation. ΔP was calculated from systolic Pas and mean Pam arterial pressures determined by volume oscillometric sphygmomanometry using the following equation: $$\Delta P = 3(P_{as} - P_{am} )/2\bar V_a $$ and the ΔV were detected by electrical admittance plethysmography at various transmural pressure Pt levels controlled by a compression cuff. The values obtained in these limb segments were compared with each other at Pt levels 0,30 and 60 mm Hg and the differences between them were discussed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 23 (1985), S. 43-47 
    ISSN: 1741-0444
    Keywords: Admittance plethysmography ; Arterial compliance ; Arterial volume ; Vascular unloading technique ; Volume elastic modulus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Static and dynamic (beat-to-beat) arterial viscoelastic properties were measured noninvasively in human fingers and forearms. The volume change and pressure change were detected simultaneously by admittance plethysmography and by sphygmomanometry using the vascular unloading technique in the index and middle finger, or vice versa. These simultaneous measurements were also made on the forearms of one side and the fingers of the other side. The arterial viscoelastic properties in these segments could be successfully determined at different transmural pressure levels from 0 mm Hg to around the mean arterial pressure.
    Type of Medium: Electronic Resource
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