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  • Temporary threshold shift  (3)
  • Inner ear  (2)
  • Local vibration exposure  (2)
  • Alpha amylase  (1)
  • Amylase  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 1202 (1993), S. 129-134 
    ISSN: 0167-4838
    Keywords: (Pancreas) ; Alpha amylase ; Amylase ; Enzyme modification ; Substrate specificity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 69 (1996), S. 45-52 
    ISSN: 1432-1246
    Keywords: Key words Vibratory sensation ; Vibration exposure ; Threshold shift ; Temporary threshold shift ; Gripping force
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract ⋅Objective This study examines the effect of the force with which a vibrating handle is gripped on the temporary threshold shift of vibratory sensation (TTSv) induced by hand-arm vibration. ⋅  Methods Six healthy subjects gripped a handle vibrating with a 1/3 octave-band vibration, with a central frequency of 200 Hz and an intensity of 39.2 m/s2. Exposure was for 1 min and 10 min, respectively. Gripping forces for the 1-min exposure were 5 N, 10 N, 40 N and 80 N, respectively, with 0 N push-pull force. Gripping forces for the 10-min exposure were the same as for the 1-min exposure, but omitting 80 N. The vibratory sensation threshold at 125 Hz was measured before and after exposure of an exposed fingertip to vibration. The differences measured determine TTS v,t at time t. TTS v,t determines TTSv,0, that is, the temporary threshold shift of vibratory sensation immediately after exposure to vibration according to the estimate made on the basis of the preceding study. The same experimental conditions were repeated 3 times on different days in a soundproof and thermoregulated room. ⋅  Results Our findings show that TTSv increases significantly with increasing gripping force. We also determined the quantitative relationships between TTSv,0 and gripping force as described by the equation where k f and c f are constants and F is gripping force. ⋅  Conclusion This study revealed the importance of ergonomic design in reducing the force with which a vibrating handle is gripped to prevent an adverse effect of local vibration. The equation devised may help in the quantitative assessment of the effect of reduced gripping force.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 68 (1996), S. 255-261 
    ISSN: 1432-1246
    Keywords: Vibratory sensation ; Local vibration exposure ; Temporary threshold shift ; Broad-band vibration ; Vibration syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight healthy subjects were exposed to three 1/3 octave-band vibrations (63, 200, and 500 Hz) by hand clasping a vibrated handle in a soundproof and thermoregulated room. The vibratory sensation threshold at 125 Hz was measured before and after the vibration exposure at an exposed fingertip. According to a preceding study, we first determined the relationship between the acceleration of the vibration and the temporary threshold shift of vibratory sensation immediately after the vibratory exposure (TTSv, 0) induced by 1/3 octave-band vibration. We then measured TTSv after the exposure to a composite vibration composed of two 1/3 octave-band vibrations that might induce an equal magnitude of TTSv, 0 on the basis of the above relationship. The TTSv, 0 induced by the composite vibration was not larger than the TTSv, 0 induced by the component vibrations. This result suggests that the component of the vibration inducing the largest TTSv, 0 determines the TTSv, 0 by broad-band random vibration.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 68 (1996), S. 255-261 
    ISSN: 1432-1246
    Keywords: Key words Vibratory sensation ; Local vibration exposure ; Temporary threshold shift ; Broad-band vibration ; Vibration syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight healthy subjects were exposed to three 1/3 octave-band vibrations (63, 200, and 500 Hz) by hand clasping a vibrated handle in a soundproof and thermoregulated room. The vibratory sensation threshold at 125 Hz was measured before and after the vibration exposure at an exposed fingertip. According to a preceding study, we first determined the relationship between the acceleration of the vibration and the temporary threshold shift of vibratory sensation immediately after the vibratory exposure (TTSv,0) induced by 1/3 octave-band vibration. We then measured TTSv after the exposure to a composite vibration composed of two 1/3 octave-band vibrations that might induce an equal magnitude of TTSv,0 on the basis of the above relationship. The TTSv,0 induced by the composite vibration was not larger than the TTSv,0 induced by the component vibrations. This result suggests that the component of the vibration inducing the largest TTSv,0 determines the TTSv,0 by broad-band random vibration.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 248 (1991), S. 479-482 
    ISSN: 1434-4726
    Keywords: Inner ear ; Human fetus ; Laminin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The expression of laminin was analyzed in the human fetal inner ear using immunohistochemical methods. In the 11-week-old human fetus, the presence of laminin was found in the basement membrane of the immature cochlea, endolymphatic sac and vestibular end organs. The reaction of the basement membrane of the endolymphatic sac was strong in the 15-week-old human fetus. A laminin reaction was seen in the cochlea, Reissner's membrane, epithelial cells of the limbus spiralis, the basilar membrane and the stria vascularis. In particular, the capillaries and basement membrane of the stria vascularis were strongly positive. These results suggest that laminin may be an essential component in the development of the inner ear and may possibly be related to filtration of the endolymph.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 252 (1995), S. 312-315 
    ISSN: 1434-4726
    Keywords: S-100 protein ; Inner ear ; Human fetus Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The expression of S-100 protein was analyzed in the human fetal inner ear using immunohistochemical methods. In the 11-week-old human fetus, the cochlea was almost negative for S-100 protein, whereas in the 14- and 15-week-old fetuses, the spiral ligament, Reissner's membrane and spiral limbus were positive for the protein. These results suggest that S-100 protein may be a reliable marker for determining functional maturation of the fetal cochlea and the inner ear. In the l l-, 14- and 15-week fetuses, the epithelial cells of the endolymphatic sac were labelled with S-100 protein. These findings demonstrate that the endolymphatic sac, spiral limbus and spiral ligament in the fetal inner ear have a high activity of S-100 protein, with this presence possibly related to fluid and ion transport of endolymph.
    Type of Medium: Electronic Resource
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