ISSN:
1432-2072
Keywords:
Physostigmine treatment
;
Alzheimer's disease
;
Regional cerebral blood flow (rCBF)
;
EEG
;
Psychometric testing
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Ten patients with Alzheimer's disease were treated with intravenous infusion of physostigmine for 2 h. The acute effects on cognitive function, regional cerebral blood flow, and EEG were compared to placebo (isotonic glucose) using a double-blind cross-over design. Physostigmine causes a limited improvement of psychomotor performance and EEG and an increase of blood flow in the most severely affected cortical areas, predominantly in an early phase of Alzheimer's disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02439583
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