ISSN:
1573-6903
Keywords:
Amino acid uptake
;
chicks
;
lizards
;
brain slices
;
sodium dependence
;
transport
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The uptake of seven amino acids, α-aminoisobutyric acid (AIB), cyclo-leucine (cyclo-Leu), γ-aminobutyric acid (GABA), glycine (Gly), glutamic acid (Glu), lysine (Lys), and taurine (Tau), representatives of different amino acid transport systems, was studied in slices of brain from Tokay lizards and White Leghorn chicks. In descending order, the rate of the initial uptake of the amino acids in both species was Glu〉Gly〉GABA〉Cyclo-Leu〉AIB〉Lys〉Tau. The substrate specificities and the differences in sodium and temperature dependence of the uptake of the amino acids indicate the presence of several distinct amino acid transport systems, some sodium-dependent and some sodium-independent. The structural specificity of amino acid transport classes in the brain of these species is similar to that in other vertebrate brain preparations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00965681
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