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  • Amitriptyline  (1)
  • Antiparkinson treatment  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 71 (1980), S. 29-34 
    ISSN: 1432-2072
    Keywords: Tardive dyskinesia ; Out-patient schizophrenics ; Neuroleptics ; Antiparkinson treatment ; EST in schizophrenia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract One hundred and twenty-two patients comprising 82% of the non-hospitalized schizophrenic population of a Hungarian town were rated for tardive dyskinesia (TD). Drug histories were also obtained. No severe cases of TD were found. The markedly lower prevalence of TD in the study population in contrast to similar North American samples may be related to differences in treatment styles, in particular to: a) use of EST in place of high-dose neuroleptic therapy; b) extensive exposure to ethopropazine, promethazine, and other antiparkinson drugs. Twenty patients revealed clinically evident fine tremors, mostly of the tongue and eye-lid. Multivariate analysis revealed a positive association of choreiform dyskinesia with duration of low-potency neuroleptic treatment.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 82 (1984), S. 256-257 
    ISSN: 1432-2072
    Keywords: Amitriptyline ; Antimuscarinic ; Catecholamines ; Positive chronotropy ; Aging ; Norepinephrine ; Angina ; Sinus heart rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Amitriptyline (AT) increases sinus heart rate (SHR) due to inhibition of the reuptake of norepinephrine in combination with an antimuscarinic blockade of cardiac vagal inhibition. After 150 mg/day AT for 28 days, the change in SHR was negatively correlated with age in 42 depressed patients who were 18–85 years of age. This finding is consistent with observations that the tachycardic response to antimuscarinics and catecholamines decreases with aging.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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