ISSN:
1432-2013
Keywords:
Pufmonary stretch receptors
;
Irritant (deflation) receptors
;
Ammonia vapour
;
Reflex tachypnoea
;
Inflation reflex
;
Pattern of breathing
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The contribution of pulmonary stretch receptor (SR) activity to the changes in breathing pattern (f,V T,t I,t E,t I:t E) following inhalation of ammonia vapour has been studied in rabbits at three levels of lung distension, i.e., three levels of SR activity, and during reversible SO2-blockade of SR. The results show that the increase in breathing frequency (f) and the decrease in tidal volume (V T) due to ammonia inhalation are almost identical for animals with and without blockade of SR, whereas the duration of inspiration and expiration (t I,t E) as well as their relationship (t I:t E) vary considerably, the variations dependeing on the level of SR activity. For a givent I the expiration was longer in animals with SR intact than in animals with SR blocked. It is concluded that in rabbits the increased activity of SR after inhalation of ammonia counteracts significantly the predominant effects of irritant (deflation) receptor stimulation, thus rendering possible a longer expiration.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00584311
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