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Screening for postnatal depression in women of non-English speaking background (1999)

Barnett, B. ; Matthey, S. ; Gyaneshwar, R.

Springer

Archives of women's mental health 2 (1999), S. 67-74

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ISSN: 1435-1102

Keywords: Keywords: Postnatal depression; non-English speaking background; Edinburgh Postnatal Depression Scale.

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Translations into Vietnamese and Arabic of the Edinburgh Postnatal Depression Scale (EPDS) were assessed to determine usefulness, acceptability and validity. Women of Arabic-speaking, Vietnamese and Anglo-Celtic background were recruited antenatally and interviewed at six weeks and six months postpartum. At each stage they completed translated versions of the EPDS and a General Health Questionnaire-30. At the two postpartum interviews, the anxiety and depression modules of the Diagnostic Interview Schedule (DIS) were completed in the appropriate language. There were no significant differences among the three groups on the EPDS, but the Vietnamese and Arabic-speaking women scored significantly higher than the Anglo-Celtic subjects on the GHQ. Fewer Vietnamese mothers met criteria for major depression or anxiety disorder, and this difference was significant at six months postpartum. The EPDS translations were acceptable to the women and appear to be suitable screening instruments for postnatal distress and depression in these populations. Threshold scores for screening purposes are discussed, but a definitive statement in this regard must await further research.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s007370050038

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Genotyping of forensic short tandem repeat (STR) systems based on sizing precision in a capillary electrophoresis instrument (1998)

Lazaruk, Katherine ; Walsh, P. Sean ; Oaks, Frank ; [et al.]

Weinheim : Wiley-Blackwell

Electrophoresis 19 (1998), S. 86-93

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ISSN: 0173-0835

Keywords: Capillary electrophoresis ; Forensic ; Short tandem repeats ; Genotyping ; AmpFlSTR ; Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Automated fluorescence analysis of polymerase chain reaction (PCR)-amplified short tandem repeat (STR) systems by capillary electrophoresis (CE) is becoming an established tool both in forensic casework and in the implementation of both state and national convicted offender DNA databases. A new capillary electrophoresis instrument, the ABI Prism 310 Genetic Analyzer, along with the Performance Optimized Polymer 4 (POP-4) provides an automated and precise method for simultaneously analyzing ten flourescently labeled STR loci from a single PCR amplification kit, which provides a power of discrimination of approximately one in five billion from a single PCR amplification. Data are presented on sizing precision, sizing accuracy, and resolution for the STR loci in the AmpFlSTR Profiler™ kit. Sizing accuracy is highly dependent on the electrophoresis system, and therefore the reporting of alleles based on the nucleotide size obtained from an electrophoresis system is not recommended for forensic work. The precision of the 310 capillary electrophoresis system, coupled with software developed for automated genotyping of alleles based on the use of an allelie ladder, allows for accurate genotyping of STR loci. Sizing precision of ≤ 0.16 nucleotide standard deviation was obtained with this system, thus allowing for accurate genotyping of length variants that differ in length by a single nucleotide.

Additional Material: 3 Ill.