Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Polymer and Materials Science  (3)
  • Amyloid β/A4 protein  (2)
  • Column liquid chromatography  (2)
  • [abr] pCMB; p-chloromercuric benzoate  (2)
  • 1
    Electronic Resource
    Electronic Resource
    In vitro autodegradation of ribosomal RNA formation of specific fragments with endonucleolytic cleavages
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 62 (1975), S. 176-183 
    Details
    ISSN: 0006-291X
    Keywords: [abr] SDS; sodium dodecylsulfate ; [abr] pCMB; p-chloromercuric benzoate
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(75)80120-3
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    In vitro autodegradation of ribosomal RNA formation of specific fragments with endonucleolytic cleavages
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 62 (1975), S. 176-183 
    Details
    ISSN: 0006-291X
    Keywords: [abr] SDS; sodium dodecylsulfate ; [abr] pCMB; p-chloromercuric benzoate
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/S0006-291X(75)80120-3
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Ultrastructure of diffuse plaques in senile dementia of the Alzheimer type: comparison with primitive plaques (1991)
    Springer
    Acta neuropathologica 82 (1991), S. 13-20 
    Details
    ISSN: 1432-0533
    Keywords: Alzheimer-type dementia ; Senile plaques ; Amyloid β/A4 protein ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We compared the ultrastructure between diffuse and primitive plaques in the brains of senile dementia, using pairs of routine electron microscopic ultrathin sections and adjacent semithin sections, which were immunolabeled for β protein. In the frontal cortex, amyloid fibrils were rarely seen in a minority of diffuse plaques, suggesting an initial stage of the diffuse plaques. A majority of the diffuse plaques had electrondense material and/or amyloid fibrils between cell processes in part of but not the entire β/A4-immunoreactive areas. Small degenerating neurites were often seen with apparent amyloid fibrils in the diffuse plaques, and these were considered to be in an advanced stage. The size and number of degenerating neurites were proportional to the amount of amyloid. Bundles of amyloid fibrils were occasionally surrounded by astroglial processes forming gap junctions. Neurons were found within some diffuse plaques, but capillaries were rarely seen. In contrast, in the temporal cortex, the diffuse plaques were smaller, and even these small ones had apparent amyloid fibrils. The amount of amyloid correlated significantly with plaque size in the temporal cortices, but not in the frontal cortices. Most of the diffuse plaques of the frontal lobe remained as advanced diffuse plaques (apparent amyloid with occasional astroglia and some degenerating neurites) for a long time, and did not transformed into primitive plaques, whereas the temporal diffuse plaques tended to transform into primitive plaques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00310918
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Extracellular neurofibrillary tangles associated with degenerating neurites and neuropil threads in Alzheimer-type dementia (1991)
    Springer
    Acta neuropathologica 81 (1991), S. 603-609 
    Details
    ISSN: 1432-0533
    Keywords: Alzheimer-type dementia ; Neurofibrillary tangles ; Neuropil threads ; Amyloid β/A4 protein ; Astroglia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We examined the cellular components of extracellular neurofibrillary tangles (E-NFT) in the hippocampal areas in cases with Alzheimer-type dementia. Immunohistochemically, the E-NFT were labeled for the C terminus of tau and glial fibrillary acidic protein. Moreover, the majority of the E-NFT was associated with intensely argyrophilic rods and with tau-and ubiquitin-immunoreactive dots. Ultrastructurally, the E-NFT consisted mainly of extracellular paired helical filaments (PHF) and astroglial processes. The extracellular PHF tended to be straighter and thinner. One third of the E-NFT was associated with small degenerating neurites containing many dense bodies and with neuropil threads containing PHF. These findings suggested that extracellular PHF promote both intense astroglial reaction and neuritic alteration, and that the E-NFT are continuously changing their morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296369
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Direct enantiomeric separation of racemic precursors to diltiazem hydrochloride and clentiazem maleate by HPLC on a chiral ovomucoid column (1993)
    Springer
    Chromatographia 35 (1993), S. 305-310 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Enantiomer separation ; Chiral ovomucoid column ; Diltiazem hydrochloride ; Clentiazem maleate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A direct HPLC separation method was developed for the determination of the enantiomers of racemic precursors to diltiazem (I) and its 8-chloro derivatives (II). The enantiomers were successfully separated on a chiral ovomucoid column using an aqueous-organic mobile phase (reversed-phase HPLC). The influence of the organic modifier and buffer pH on the retention and enantioselectivity was investigated. The chromatographic conditions chosen for the separation permitted complete resolution of the enantiomers of both the acid (Ib and IIb) and methyl ester precursors (Ia and IIa) within 20 min. The influence of sample load on retention times, theoretical plates numbers, peak heights and peak areas was also investigated. The peak areas showed a good linearity over the concentration range examined, although all the others were influenced significantly by the sample size. An optical antipode of the intermediate to be determined could be detected by the area-percentage method down to ca. 0.1%, together with the determination of its precursor, including its optical purity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02277515
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Synthese und eigenschaften einiger höhergliedriger cyclischer ätheracetale (1977)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 178 (1977), S. 3191-3195 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Optimized syntheses of 1,3,6,9-tetraoxacycloundecane (2), 1,3,6,9,12-pentaoxacylotetradecane (3), and 1,3,6,9,12,14,17,20-octaoxacyclodocosane (4) as well as some physical and chemical properties and the proof of structure are reported.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1977.021781202
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Preparation and characterization of macroporous polystyrene resins containing ethynyl groups and transition metal acetylide complexes (1987)
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 25 (1987), S. 2281-2288 
    Details
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Ethynylated polystyrene resins were prepared as functionalized polymer supports by the iodination reaction of macroporous polystyrene resins and reacted with transition metal diethynyl complex (Mt = Ni) and metal halides (Mt = Rh, Pd, and Pt) in a basic solvent using cuprous iodide as a catalyst to obtain macroporous polystyrene resins containing organotransition metals. The distribution of the metal acetylide complexes in the modified macroporous resins was determined by an electron probe microanalyzer. A gradient in the transition metal distribution was observed in any case of the modified resins. The stability of the organotransition metal complexes in the polymer matrix could be compared with a low molecular weight analogous complex quantitatively.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pola.1987.080250824
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Reversed-phase HPLC separation of the enantiomers of denopamine after derivatization with GITC chiral reagent (1990)
    Springer
    Chromatographia 30 (1990), S. 186-190 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Enantiomer separation ; Denopamine ; Derivatization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A reversed-phase high-performance liquid chromatographic (HPLC) method was developed to determine the optical purity of denopamine, which is a new cardiotonic agent having an asymmetric carbon in a molecule. The enantiomers were converted to diastereomeric thiourea derivatives using 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate (GITC) reagent. Separation of the enantiomers of denopamine as diastereomers was successfully achieved by reversed-phase HPLC within 10 min using an ODS column and UV detection. Derivatization of denopamine proceeded rapidly under the alkaline conditions and the ambient temperature. This method was applied to the determination of the optical purity of denopamine drug substances and those in tablets. The favorable UV absorption of the derivatives enabled the optical antipode to be determined down to the 0.2% level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02274544
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Adsorption mechanism of heavy-metal ion by microspherical tannin resin (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 45 (1992), S. 1463-1472 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The spherical tannin resin (STR) resulting from the reaction between Mimosa (Acacia Mollissima) tannin (condensed-type tannin) and formaldehyde was very porous. The specific surface area of the STR made from 37.5% of tannin was 139.2 m2/g (1 g of the resin in this is wet resin corresponding to 1 g of dried resin). Properties such as specific surface area and average pore radius could be controlled by adjusting the tannin concentration. The apparent activation energy of Cu2+ ion adsorption by STR was 3 kcal/mol, and that of Cr6+ ion was 2 kcal/mol. Since the energy was small, we concluded that the adsorption of metal ions was not influenced significantly by the adsorption temperature. The heat of adsorption for Cu2+ ions was only 1.6 kcal/mol, which suggests that the adsorption was a physical phenomenon. It was thought that the diffusion of heavy-metal ions into the porous resin was the rate-determining step of the adsorption since the elution profile of the column method was analogous to the profile of active carbon, which adsorbs physically, the heavy metal ions gradually leaking through the column. The surface and cross section of the STR were observed before and after Cu2+ ion adsorption with the scanning electron microscope. The pores of the spherical resin were clogged with adsorbed copper, suggesting that the Cu2+ ions were adsorbed during the formation of a multimolecular layer. The adsorption may therefore have been due to physical attractive forces. The rate of adsorption and adsorption isotherms of Cu2+ ions from copper salts having various anions was found to vary depending on the type of anion. These phenomena were not thought to be due to the properties of the spherical resin but to differences in the hydration state of copper ions.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1992.070450815
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...